|
rdf:type |
|
|
lifeskim:mentions |
|
|
pubmed:issue |
3
|
|
pubmed:dateCreated |
1997-7-29
|
|
pubmed:abstractText |
Margination of circulating neutrophils (PMN) into the gastric microcirculation is an early and critical event in the pathogenesis of non-steroidal antinflammatory drug (NSAID)-induced gastropathy. This effect is mediated through the upregulation of beta 2 integrins on the PMN surface.
|
|
pubmed:language |
eng
|
|
pubmed:journal |
|
|
pubmed:citationSubset |
IM
|
|
pubmed:chemical |
|
|
pubmed:status |
MEDLINE
|
|
pubmed:month |
Jun
|
|
pubmed:issn |
0269-2813
|
|
pubmed:author |
|
|
pubmed:issnType |
Print
|
|
pubmed:volume |
11
|
|
pubmed:owner |
NLM
|
|
pubmed:authorsComplete |
Y
|
|
pubmed:pagination |
619-30
|
|
pubmed:dateRevised |
2007-11-15
|
|
pubmed:meshHeading |
pubmed-meshheading:9218092-Anti-Inflammatory Agents, Non-Steroidal,
pubmed-meshheading:9218092-Antigens, CD18,
pubmed-meshheading:9218092-Calcium,
pubmed-meshheading:9218092-Cell Count,
pubmed-meshheading:9218092-Humans,
pubmed-meshheading:9218092-Indomethacin,
pubmed-meshheading:9218092-Macrophage-1 Antigen,
pubmed-meshheading:9218092-Neutrophils,
pubmed-meshheading:9218092-Nitric Oxide,
pubmed-meshheading:9218092-Peroxidase,
pubmed-meshheading:9218092-Protein Kinase C,
pubmed-meshheading:9218092-Superoxides,
pubmed-meshheading:9218092-Up-Regulation
|
|
pubmed:year |
1997
|
|
pubmed:articleTitle |
NSAIDs upregulate beta 2-integrin expression on human neutrophils through a calcium-dependent pathway.
|
|
pubmed:affiliation |
Dipartimento di Medicina Clinica, Patologia e Farmacologia, Università degli Studi di Perugia, Italy.
|
|
pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
|
