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rdf:type |
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lifeskim:mentions |
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pubmed:dateCreated |
1997-9-5
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pubmed:abstractText |
Even though the presence of a prominent tissue eosinophilia represents a common histopathologic feature of Hodgkin's disease (HD), eosinophils have been mainly regarded as 'innocent' bystanders recruited and activated during the cellular reaction typical of HD. To evaluate the putative role of eosinophils or eosinophil-derived cytokines on tumor-cell regulation in HD, we have analyzed these cells for the functional expression of surface ligands (L) of the tumor necrosis factor (TNF) superfamily, whose specific receptors are known to transduce proliferation signals at the surface of Hodgkin (H) and Reed-Sternberg (RS) cells.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:issn |
0923-7534
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pubmed:author |
pubmed-author:AldinucciDD,
pubmed-author:CarboneAA,
pubmed-author:De IuliisAA,
pubmed-author:DeganMM,
pubmed-author:GatteiVV,
pubmed-author:GloghiniAA,
pubmed-author:GrussH JHJ,
pubmed-author:ImprotaSS,
pubmed-author:PerisSS,
pubmed-author:PintoAA,
pubmed-author:SaccoCC,
pubmed-author:TodescoMM,
pubmed-author:ZagonelVV
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pubmed:issnType |
Print
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pubmed:volume |
8 Suppl 2
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
89-96
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:9209649-Antigens, CD30,
pubmed-meshheading:9209649-Antigens, CD40,
pubmed-meshheading:9209649-Antigens, Neoplasm,
pubmed-meshheading:9209649-Apoptosis,
pubmed-meshheading:9209649-Case-Control Studies,
pubmed-meshheading:9209649-Cell Division,
pubmed-meshheading:9209649-Eosinophils,
pubmed-meshheading:9209649-Hodgkin Disease,
pubmed-meshheading:9209649-Humans,
pubmed-meshheading:9209649-Ligands,
pubmed-meshheading:9209649-Receptors, Tumor Necrosis Factor,
pubmed-meshheading:9209649-Reference Values
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pubmed:year |
1997
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pubmed:articleTitle |
The role of eosinophils in the pathobiology of Hodgkin's disease.
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pubmed:affiliation |
Leukemia Unit, Centro di Riferimento Oncologico, IRCCS, Aviano, Italy.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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