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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
1
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pubmed:dateCreated |
1997-7-24
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pubmed:abstractText |
Sarcoidosis is generally characterized by a CD4+ lymphocyte predominance in bronchoalveolar lavage fluid (BALF), whereas in extrinsic allergic alveolitis (EAA) a CD8+ lymphocyte predominance is found. However, we have previously demonstrated an increase in CD4+ lymphocytes in BALF obtained from EAA patients as well. The aim of this study was to evaluate whether in sarcoidosis and EAA the BALF cellular profile-even without the help of cytokine detection-might reflect differences in the CD4+ T-lymphocyte subpopulations, i.e. T helper (TH)-1 and TH2 lymphocytes.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Mar
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pubmed:issn |
1124-0490
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
14
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
31-8
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:9186987-Adult,
pubmed-meshheading:9186987-Aged,
pubmed-meshheading:9186987-Alveolitis, Extrinsic Allergic,
pubmed-meshheading:9186987-Antibodies, Monoclonal,
pubmed-meshheading:9186987-Biopsy,
pubmed-meshheading:9186987-Bronchoalveolar Lavage Fluid,
pubmed-meshheading:9186987-Bronchoscopy,
pubmed-meshheading:9186987-CD4-CD8 Ratio,
pubmed-meshheading:9186987-CD4-Positive T-Lymphocytes,
pubmed-meshheading:9186987-CD8-Positive T-Lymphocytes,
pubmed-meshheading:9186987-Female,
pubmed-meshheading:9186987-Fluorescent Antibody Technique, Indirect,
pubmed-meshheading:9186987-Humans,
pubmed-meshheading:9186987-Leukocyte Count,
pubmed-meshheading:9186987-Male,
pubmed-meshheading:9186987-Middle Aged,
pubmed-meshheading:9186987-Sarcoidosis, Pulmonary,
pubmed-meshheading:9186987-T-Lymphocyte Subsets,
pubmed-meshheading:9186987-T-Lymphocytes, Helper-Inducer
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pubmed:year |
1997
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pubmed:articleTitle |
Is the different T helper cell activity in sarcoidosis and extrinsic allergic alveolitis also reflected by the cellular bronchoalveolar lavage fluid profile?
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pubmed:affiliation |
Department of Pulmonology, University Hospital of Maastricht, The Netherlands.
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pubmed:publicationType |
Journal Article,
Comparative Study,
Research Support, Non-U.S. Gov't
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