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| Predicate | Object |
|---|---|
| rdf:type | |
| lifeskim:mentions | |
| pubmed:issue |
3
|
| pubmed:dateCreated |
1997-7-30
|
| pubmed:abstractText |
The pharmacokinetic behaviour of dipyrone metabolite 4-MAA in serum was determined in seven horses of different breeds after a single intravenous dose administration. A biexponential formula was fitted to the serum concentration vs. time data. The median half-life of the elimination phase (t1/2 beta) was 4.85 h (range 5.04 h), the median volume of distribution (Vd(area)) was 1.85 L/kg (range 3.2 L/kg) and median of total clearance was 4.0 mL/min/kg (range 2.3 mL/min/kg).
|
| pubmed:language |
eng
|
| pubmed:journal | |
| pubmed:citationSubset |
IM
|
| pubmed:chemical | |
| pubmed:status |
MEDLINE
|
| pubmed:month |
Jun
|
| pubmed:issn |
0140-7783
|
| pubmed:author | |
| pubmed:issnType |
Print
|
| pubmed:volume |
20
|
| pubmed:owner |
NLM
|
| pubmed:authorsComplete |
Y
|
| pubmed:pagination |
204-8
|
| pubmed:dateRevised |
2006-11-15
|
| pubmed:meshHeading |
pubmed-meshheading:9185086-Animals,
pubmed-meshheading:9185086-Anti-Inflammatory Agents, Non-Steroidal,
pubmed-meshheading:9185086-Area Under Curve,
pubmed-meshheading:9185086-Dipyrone,
pubmed-meshheading:9185086-Doping in Sports,
pubmed-meshheading:9185086-Female,
pubmed-meshheading:9185086-Gas Chromatography-Mass Spectrometry,
pubmed-meshheading:9185086-Half-Life,
pubmed-meshheading:9185086-Horses,
pubmed-meshheading:9185086-Male,
pubmed-meshheading:9185086-Metabolic Clearance Rate,
pubmed-meshheading:9185086-Pyrazolones
|
| pubmed:year |
1997
|
| pubmed:articleTitle |
Pharmacokinetic study of dipyrone metabolite 4-MAA in the horse and possible implications for doping control.
|
| pubmed:affiliation |
Institut für Pharmakologie, Toxikologie und Pharmazie, Tierärztliche Hochschule Hannover, Germany.
|
| pubmed:publicationType |
Journal Article
|