Linked Life Data

9165022

Source:http://linkedlifedata.com/resource/pubmed/id/9165022

Statements in which the resource exists.
SubjectPredicateObjectContext
pubmed-article:9165022rdf:typepubmed:Citationlld:pubmed
pubmed-article:9165022lifeskim:mentionsumls-concept:C0032961lld:lifeskim
pubmed-article:9165022lifeskim:mentionsumls-concept:C0034721lld:lifeskim
pubmed-article:9165022lifeskim:mentionsumls-concept:C0034693lld:lifeskim
pubmed-article:9165022lifeskim:mentionsumls-concept:C0014442lld:lifeskim
pubmed-article:9165022lifeskim:mentionsumls-concept:C0002006lld:lifeskim
pubmed-article:9165022lifeskim:mentionsumls-concept:C0521428lld:lifeskim
pubmed-article:9165022lifeskim:mentionsumls-concept:C1280500lld:lifeskim
pubmed-article:9165022lifeskim:mentionsumls-concept:C0220781lld:lifeskim
pubmed-article:9165022lifeskim:mentionsumls-concept:C1883254lld:lifeskim
pubmed-article:9165022lifeskim:mentionsumls-concept:C2587213lld:lifeskim
pubmed-article:9165022pubmed:issue6lld:pubmed
pubmed-article:9165022pubmed:dateCreated1997-6-17lld:pubmed
pubmed-article:9165022pubmed:abstractTextIn the present study, the effects of gestation on various enzymes implicated in corticosteroid synthesis were evaluated in adrenal zona glomerulosa and zona fasciculata-reticularis of the Sprague-Dawley rat. The activity and expression of cholesterol side-chain cleavage cytochrome P450, 11beta-hydroxylase cytochrome P450, and aldosterone synthase cytochrome P450 (P450aldo) were analyzed. Plasma aldosterone levels were increased significantly at 22 days gestation (n = 10) and fell below the nonpregnant levels at 18-36 h postpartum (n = 11). The activity and expression of 11beta-hydroxylase cytochrome P450 and cholesterol side-chain cleavage cytochrome P450 were not modified by gestation. P450aldo activity increased at 14 days gestation (n = 4) and returned to the prepregnancy level at 2 weeks postpartum (n = 5). As shown by Northern blot analysis (n = 3), P450aldo messenger RNA increased significantly at 22 days gestation and decreased 18-36 h postpartum. We clearly demonstrated that elevated plasma aldosterone levels during pregnancy are associated with augmented activity and messenger RNA levels of P450aldo in the zona glomerulosa.lld:pubmed
pubmed-article:9165022pubmed:languageenglld:pubmed
pubmed-article:9165022pubmed:journalhttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:9165022pubmed:citationSubsetAIMlld:pubmed
pubmed-article:9165022pubmed:chemicalhttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:9165022pubmed:chemicalhttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:9165022pubmed:chemicalhttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:9165022pubmed:chemicalhttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:9165022pubmed:chemicalhttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:9165022pubmed:chemicalhttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:9165022pubmed:statusMEDLINElld:pubmed
pubmed-article:9165022pubmed:monthJunlld:pubmed
pubmed-article:9165022pubmed:issn0013-7227lld:pubmed
pubmed-article:9165022pubmed:authorpubmed-author:LehouxJ GJGlld:pubmed
pubmed-article:9165022pubmed:authorpubmed-author:PicardSSlld:pubmed
pubmed-article:9165022pubmed:authorpubmed-author:BrochuMMlld:pubmed
pubmed-article:9165022pubmed:issnTypePrintlld:pubmed
pubmed-article:9165022pubmed:volume138lld:pubmed
pubmed-article:9165022pubmed:ownerNLMlld:pubmed
pubmed-article:9165022pubmed:authorsCompleteYlld:pubmed
pubmed-article:9165022pubmed:pagination2354-8lld:pubmed
pubmed-article:9165022pubmed:dateRevised2006-11-15lld:pubmed
pubmed-article:9165022pubmed:meshHeadingpubmed-meshheading:9165022-...lld:pubmed
pubmed-article:9165022pubmed:meshHeadingpubmed-meshheading:9165022-...lld:pubmed
pubmed-article:9165022pubmed:meshHeadingpubmed-meshheading:9165022-...lld:pubmed
pubmed-article:9165022pubmed:meshHeadingpubmed-meshheading:9165022-...lld:pubmed
pubmed-article:9165022pubmed:meshHeadingpubmed-meshheading:9165022-...lld:pubmed
pubmed-article:9165022pubmed:meshHeadingpubmed-meshheading:9165022-...lld:pubmed
pubmed-article:9165022pubmed:meshHeadingpubmed-meshheading:9165022-...lld:pubmed
pubmed-article:9165022pubmed:meshHeadingpubmed-meshheading:9165022-...lld:pubmed
pubmed-article:9165022pubmed:meshHeadingpubmed-meshheading:9165022-...lld:pubmed
pubmed-article:9165022pubmed:meshHeadingpubmed-meshheading:9165022-...lld:pubmed
pubmed-article:9165022pubmed:meshHeadingpubmed-meshheading:9165022-...lld:pubmed
pubmed-article:9165022pubmed:meshHeadingpubmed-meshheading:9165022-...lld:pubmed
pubmed-article:9165022pubmed:meshHeadingpubmed-meshheading:9165022-...lld:pubmed
pubmed-article:9165022pubmed:meshHeadingpubmed-meshheading:9165022-...lld:pubmed
pubmed-article:9165022pubmed:meshHeadingpubmed-meshheading:9165022-...lld:pubmed
pubmed-article:9165022pubmed:meshHeadingpubmed-meshheading:9165022-...lld:pubmed
pubmed-article:9165022pubmed:meshHeadingpubmed-meshheading:9165022-...lld:pubmed
pubmed-article:9165022pubmed:meshHeadingpubmed-meshheading:9165022-...lld:pubmed
pubmed-article:9165022pubmed:meshHeadingpubmed-meshheading:9165022-...lld:pubmed
pubmed-article:9165022pubmed:meshHeadingpubmed-meshheading:9165022-...lld:pubmed
pubmed-article:9165022pubmed:year1997lld:pubmed
pubmed-article:9165022pubmed:articleTitleEffects of gestation on enzymes controlling aldosterone synthesis in the rat adrenal.lld:pubmed
pubmed-article:9165022pubmed:affiliationResearch Center, Sainte-Justine's Hospital, University of Montreal, Quebec, Canada. brochum@ere.umontreal.calld:pubmed
pubmed-article:9165022pubmed:publicationTypeJournal Articlelld:pubmed
pubmed-article:9165022pubmed:publicationTypeResearch Support, Non-U.S. Gov'tlld:pubmed
http://linkedlifedata.com/r...pubmed:referesTopubmed-article:9165022lld:pubmed