|
rdf:type |
|
|
lifeskim:mentions |
|
|
pubmed:issue |
6
|
|
pubmed:dateCreated |
1980-1-19
|
|
pubmed:abstractText |
Antigen-induced proliferation of primed lymph node cells was abrogated by treatment with anti-Ly 1 serum and complement (C) but not with anti-Ly 2 serum and C. Lymph node cells from animals primed to ovalbumin were activated with antigen in vitro, followed by propagation in an antigen-free supernatant fluid obtained from lectin-induced normal spleen cells. T cells processed in this manner displayed a stepwise enrichment of helper activity for antibody production as measured in a secondary hapten-carrier response. The sequential increase in antigen-specific help was paralleled by a rise in the antigen-induced proliferative response, a phenomenon whose expression was dependent on the presence of syngeneic or semi-syngeneic irradiated filler cells.
|
|
pubmed:language |
eng
|
|
pubmed:journal |
|
|
pubmed:citationSubset |
AIM
|
|
pubmed:chemical |
|
|
pubmed:status |
MEDLINE
|
|
pubmed:month |
Dec
|
|
pubmed:issn |
0022-1767
|
|
pubmed:author |
|
|
pubmed:issnType |
Print
|
|
pubmed:volume |
123
|
|
pubmed:owner |
NLM
|
|
pubmed:authorsComplete |
Y
|
|
pubmed:pagination |
2525-31
|
|
pubmed:dateRevised |
2006-11-15
|
|
pubmed:meshHeading |
pubmed-meshheading:91635-Animals,
pubmed-meshheading:91635-Antilymphocyte Serum,
pubmed-meshheading:91635-Complement System Proteins,
pubmed-meshheading:91635-Concanavalin A,
pubmed-meshheading:91635-Culture Media,
pubmed-meshheading:91635-Dinitrobenzenes,
pubmed-meshheading:91635-Epitopes,
pubmed-meshheading:91635-Hemocyanin,
pubmed-meshheading:91635-Hemolytic Plaque Technique,
pubmed-meshheading:91635-Humans,
pubmed-meshheading:91635-Lymph Nodes,
pubmed-meshheading:91635-Lymphocyte Activation,
pubmed-meshheading:91635-Lymphocyte Culture Test, Mixed,
pubmed-meshheading:91635-Major Histocompatibility Complex,
pubmed-meshheading:91635-Mice,
pubmed-meshheading:91635-Mice, Inbred A,
pubmed-meshheading:91635-Mice, Inbred C57BL,
pubmed-meshheading:91635-Mice, Inbred DBA,
pubmed-meshheading:91635-Ovalbumin,
pubmed-meshheading:91635-T-Lymphocytes,
pubmed-meshheading:91635-gamma-Globulins
|
|
pubmed:year |
1979
|
|
pubmed:articleTitle |
Propagation of antigen-specific T cell helper function in vitro.
|
|
pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, P.H.S.
|
