Linked Life Data

9158269

Source:http://linkedlifedata.com/resource/pubmed/id/9158269

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
1
pubmed:dateCreated
1997-6-17
pubmed:abstractText
Promethazine hydrochloride is known to possess properties as a local anaesthetic which scientists have not researched well. Therefore, a prospective, randomised, double-blind clinical study was conducted to evaluate the efficacy of promethazine hydrochloride compared to lignocaine hydrochloride, when used as a local anaesthetic agent. Twenty adult male patients undergoing inguinal hernia repair were included in the study. Regional nerve block technique was employed in all the patients. Efficacy of the agents was assessed on a four-point scale and by recording the pulse and the blood pressure. Promethazine hydrochloride was found to be as effective as lignocaine hydrochloride in terms of the intensity and the duration of regional anaesthesia produced. None of the patients from either group required additional anaesthesia in any form, and no complications were witnessed. To conclude, promethazine hydrochloride appears to be a safe alternative to lignocaine hydrochloride for performing surgery under regional anaesthesia.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:issn
0007-0947
pubmed:author
pubmed:issnType
Print
pubmed:volume
51
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
33-5
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:articleTitle
Efficacy and safety of promethazine hydrochloride as a local anaesthetic agent for inguinal hernia repair: a pilot study.
pubmed:affiliation
Guru Teg Bahadur Hospital, University College of Medical Sciences, Delhi, India.
pubmed:publicationType
Journal Article, Clinical Trial, Comparative Study, Randomized Controlled Trial