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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
1-2
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pubmed:dateCreated |
1997-6-26
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pubmed:abstractText |
The structure of the Y chromosome was investigated by FISH and G banding in 3 cases of bovine XY females shown by PCR to lack the SRY gene. Although 2 different repeat-DNA sequences (BC1.2 and btDYZ-1) hybridized to the short arm of the Y chromosome in a normal bull, they hybridized to both arms of the Y chromosome in the XY females. In the Y chromosome from XY females, only the centromeric region was darkly stained by G banding, in comparison with dark staining on the long arm of a normal Y chromosome. From the results obtained, it seemed that the Y chromosome from the XY females was structurally abnormal, namely an isochromosome with an identical short arm. Our results also confirm that SRY is located on the long arm of the Y chromosome in bovine.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:issn |
0301-0171
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
76
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
36-8
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pubmed:dateRevised |
2005-11-17
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pubmed:meshHeading |
pubmed-meshheading:9154121-Animals,
pubmed-meshheading:9154121-Cattle,
pubmed-meshheading:9154121-Cattle Diseases,
pubmed-meshheading:9154121-Chromosome Deletion,
pubmed-meshheading:9154121-DNA-Binding Proteins,
pubmed-meshheading:9154121-Female,
pubmed-meshheading:9154121-Gonadal Dysgenesis, 46,XY,
pubmed-meshheading:9154121-In Situ Hybridization, Fluorescence,
pubmed-meshheading:9154121-Nuclear Proteins,
pubmed-meshheading:9154121-Sex-Determining Region Y Protein,
pubmed-meshheading:9154121-Transcription Factors,
pubmed-meshheading:9154121-Y Chromosome
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pubmed:year |
1997
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pubmed:articleTitle |
Abnormal structure of the Y chromosome detected in bovine gonadal hypoplasia (XY female) by FISH.
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pubmed:affiliation |
National Institute of Animal Industry, Tsukuba, Japan.
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pubmed:publicationType |
Journal Article
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