Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
5
pubmed:dateCreated
1997-7-22
pubmed:abstractText
The effects of active immunization against peripheral insulin beta subunits on different sleep variables and food consumption were studied in rats. Insulin subunits beta coupled to thyroglobulin was used as immunogen and rats immunized with thyroglobulin alone served as controls. Active immunization against insulin beta subunits affects sleep variables, particularly slow-wave sleep during the dark period, increasing significantly this stage of sleep and decreasing waking. Feeding behavior and body weight remained unchanged. These results are compatible with previous studies showing a positive correlation between decrease of insulin secretion and sleep disturbances. A possible relationship between peripheral alpha and or beta subunits of insulin, sleep, and feeding is suggested.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
May
pubmed:issn
0031-9384
pubmed:author
pubmed:issnType
Print
pubmed:volume
61
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
649-51
pubmed:dateRevised
2011-11-17
pubmed:meshHeading
pubmed:year
1997
pubmed:articleTitle
Active immunization of rats against insulin beta subunits: effects on sleep and feeding.
pubmed:affiliation
Hospital University of Geneva (HUG), Division of Neuropsychiatry, Chêne-Bourg, Switzerland.
pubmed:publicationType
Journal Article