Linked Life Data

9135374

Source:http://linkedlifedata.com/resource/pubmed/id/9135374

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
2
pubmed:dateCreated
1997-5-15
pubmed:abstractText
The purpose of the present experiments was to extend previous data on the strategy used by adult rats to select feed appropriately when faced with diets devoid of protein or an essential amino acid (EAA), and to compare this strategy with that used when facing vitamin (thiamin) deficiency. Rats fed on either balanced or deficient (EAA or protein) diets were offered a choice between a novel deficient and a familiar (deficient or corrected) diet and their choice was monitored. It was shown that protein- and EAA-deficient rats acquired an aversion for their corresponding familiar devoid diet, which by itself promoted a neophilia for the novel diet. This neophilia was not non-specific because protein-deficient rats facing a choice between a protein-devoid and an EAA-devoid diet did exhibit neophilia but only in the short term (less than 5 h), and then switched to a preference for the familiar protein-devoid diet. These results show that, in contrast to the case of vitamin deficiency, the protein- or EAA-devoid diet-induced neophilia can be rapidly reversed if the novel feed happens to be more deleterious than the familiar, inappropriate one. This behaviour suggests the existence of sensitive mechanisms able to reveal within a short time the EAA inadequacy of the ingested feed and to adapt the choice for the most appropriate feeds more promptly than in the face of thiamin deficiency. Thus it appears that balancing EAA is more urgent than balancing thiamin.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Feb
pubmed:issn
0007-1145
pubmed:author
pubmed:issnType
Print
pubmed:volume
77
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
299-314
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
1997
pubmed:articleTitle
Aversion-preference patterns in amino acid- or protein-deficient rats: a comparison with previously reported responses to thiamin-deficient diets.
pubmed:affiliation
Laboratoire de neurobiologie des régulations, CNRS UPR 9054, Collège de France, Paris, France.
pubmed:publicationType
Journal Article, Comparative Study