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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:dateCreated |
1997-7-16
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pubmed:abstractText |
The role that the Calcium Sensing Receptor (CASR) plays in extracellular calcium regulation had been ascertained through studies of inactivating as well as activating mutations of CASR gene in a number of multiplex families. We have extended these observations to a polymorphism analysis of the intercellular domain of CASR in a cohort of healthy young women. The results demonstrate significant allelic polymorphism as a result of nonconservative changes at two specific sites. Further studies will be required to determine what, if any, relationship this may have to CASR phenotype.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:issn |
0085-591X
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
227
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
122-5
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pubmed:dateRevised |
2004-11-17
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pubmed:meshHeading |
pubmed-meshheading:9127478-Adolescent,
pubmed-meshheading:9127478-Adult,
pubmed-meshheading:9127478-Alleles,
pubmed-meshheading:9127478-Calcium,
pubmed-meshheading:9127478-Cohort Studies,
pubmed-meshheading:9127478-Female,
pubmed-meshheading:9127478-Gene Frequency,
pubmed-meshheading:9127478-Humans,
pubmed-meshheading:9127478-Polymorphism, Genetic,
pubmed-meshheading:9127478-Receptors, Cell Surface
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pubmed:year |
1997
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pubmed:articleTitle |
Calcium sensing receptor gene: analysis of polymorphism frequency.
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pubmed:affiliation |
Department of Medicine, University of Toronto, Canada.
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pubmed:publicationType |
Journal Article,
Multicenter Study
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