Linked Life Data

9121087

Source:http://linkedlifedata.com/resource/pubmed/id/9121087

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
9
pubmed:dateCreated
1997-4-22
pubmed:abstractText
Antiphospholipid syndrome (APLS) is a clinicolaboratory symptom complex characterized by development of venous and/or arterial thromboses, thrombocytopenia, obstetric pathology arising in the presence of hyperproduction of antiphospholipid antibodies (APAB). APLS may occur not only in patients with systemic lupus erythematosus (SLE) or other autoimmune diseases as secondary APLS, but in those without the above diseases as the primary APLS. The authors have examined 34 patients with APLS versus 10 patients with a verified SLE free of APLS manifestations. Affection of the valves was found in 30 patients with APLS (88%). More frequent were additional structures on mitral and aortic valve cusps, thickening of mitral valve cusps in APLS patients. Evident valvular disease was seen only in APLS patients with high positive levels of APAB. Valvular lesions were similar in patients with primary and secondary APLS. The study has revealed a relationship between the presence of antibodies to phospholipids and valvular abnormalities in APLS patients.
pubmed:language
rus
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:issn
0023-2149
pubmed:author
pubmed:issnType
Print
pubmed:volume
74
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
39-42
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
1996
pubmed:articleTitle
[Involvement of cardiac valves in antiphospholipid syndrome].
pubmed:affiliation
Scientific Cardiological Center KNTs RAMN, Moscow.
pubmed:publicationType
Journal Article, Comparative Study, English Abstract