Switch to
Predicate | Object |
---|---|
rdf:type | |
lifeskim:mentions | |
pubmed:issue |
4
|
pubmed:dateCreated |
1997-6-11
|
pubmed:abstractText |
The thromboelastogram (TEG) measures functional defects in coagulation, from fibrin formation through platelet aggregation to fibrinolysis. It is comparable with standard laboratory tests of coagulation; however, it provides additional useful qualitative information. This prospective study documents the TEG findings in 103 neonates: 60 were normal and healthy and provided a reference range; 12 surgical babies had established sepsis, 15 had early sepsis, and 16 were non-septic. TEG abnormalities were detected only in those patients with early and established sepsis. Abnormalities were found in all but 1 of this group of 27 patients (96%), whereas only 16 (59%) had thrombocytopenia, 2 (6%) had leukocytosis, and 6 had leukopenia. The TEG had a sensitivity for sepsis of 96% and a specificity of 96%. This exceeds the values for routine full blood-count parameters and other laboratory indicators of sepsis. It was found to be a simple, quick, and sensitive indicator of early sepsis that enabled the clinicians to manage septic newborns earlier.
|
pubmed:language |
eng
|
pubmed:journal | |
pubmed:citationSubset |
IM
|
pubmed:status |
MEDLINE
|
pubmed:month |
Apr
|
pubmed:issn |
0179-0358
|
pubmed:author | |
pubmed:issnType |
Print
|
pubmed:volume |
12
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
289-92
|
pubmed:dateRevised |
2004-11-17
|
pubmed:meshHeading |
pubmed-meshheading:9099648-Blood Cell Count,
pubmed-meshheading:9099648-Case-Control Studies,
pubmed-meshheading:9099648-Humans,
pubmed-meshheading:9099648-Infant, Newborn,
pubmed-meshheading:9099648-Predictive Value of Tests,
pubmed-meshheading:9099648-Prospective Studies,
pubmed-meshheading:9099648-Sensitivity and Specificity,
pubmed-meshheading:9099648-Sepsis,
pubmed-meshheading:9099648-Thrombelastography
|
pubmed:year |
1997
|
pubmed:articleTitle |
Prediction of neonatal sepsis by thromboelastography.
|
pubmed:affiliation |
Department of Paediatric Surgery, University of Natal, P. O. Box 17039, Congella 4013, Natal, South Africa.
|
pubmed:publicationType |
Journal Article
|