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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
6
|
pubmed:dateCreated |
1997-4-8
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pubmed:abstractText |
The overall survival rate for patients with neuroblastoma has improved over the past two decades, but long-term survival for the subgroup of patients with high-risk disease remains low. In recent years, there has been interest in the potential clinical use of drugs able to induce differentiation of neuroblastoma cells. Since 9-cis-retinoic acid induces better and more sustained differentiation of neuroblastoma in vitro than other retinoic acid isomers, this may be a more appropriate retinoid for use in neuroblastoma therapy.
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pubmed:language |
eng
|
pubmed:journal | |
pubmed:citationSubset |
IM
|
pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Mar
|
pubmed:issn |
0027-8874
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:day |
19
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pubmed:volume |
89
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
|
pubmed:pagination |
446-52
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:9091647-Antineoplastic Agents,
pubmed-meshheading:9091647-Apoptosis,
pubmed-meshheading:9091647-DNA Nucleotidylexotransferase,
pubmed-meshheading:9091647-Flow Cytometry,
pubmed-meshheading:9091647-Immunoenzyme Techniques,
pubmed-meshheading:9091647-Neuroblastoma,
pubmed-meshheading:9091647-Time Factors,
pubmed-meshheading:9091647-Tretinoin,
pubmed-meshheading:9091647-Tumor Cells, Cultured
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pubmed:year |
1997
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pubmed:articleTitle |
Apoptosis of N-type neuroblastoma cells after differentiation with 9-cis-retinoic acid and subsequent washout.
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pubmed:affiliation |
Department of Medicine, University of Newcastle Upon Tyne, U.K.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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