Linked Life Data

9079748

Source:http://linkedlifedata.com/resource/pubmed/id/9079748

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
1
pubmed:dateCreated
1997-8-13
pubmed:abstractText
The influence of old age on mechanical properties of the urinary bladder was investigated using smooth muscle strips from urinary bladders of control (14-16 weeks) and old-age (104 weeks) female Sprague-Dawley rats. Bladder weight of the aged rats had increased by about 30%. The maximal shortening velocity and stiffness in skinned activated urinary bladder fibers from old animals were unchanged compared to controls. The relative content of intermediate filament proteins to actin and the relative content of myosin to actin was unchanged. The concentration of myosin was unchanged (about 6.5 microg/mg wet weight). The results suggest that old age is not associated with pronounced changes in the cellular contractile and cytoskeletal proteins or in the mechanical properties of the contractile machinery. The age-related changes in mechanical properties previously reported for intact smooth muscle from urinary bladder are most likely due to alterations in the activation systems.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:issn
0300-5623
pubmed:author
pubmed:issnType
Print
pubmed:volume
25
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
67-70
pubmed:dateRevised
2009-11-19
pubmed:meshHeading
pubmed:year
1997
pubmed:articleTitle
Old age does not affect shortening velocity or content of contractile and cytoskeletal proteins in the rat detrusor smooth muscle.
pubmed:affiliation
Department of Physiology and Neuroscience, Lund University, Sweden.
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't