Linked Life Data

9072852

Source:http://linkedlifedata.com/resource/pubmed/id/9072852

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
8
pubmed:dateCreated
1997-3-25
pubmed:abstractText
Thyroid stimulating antibodies (TSAb) are thought to be involved in the initiation of Graves' disease, and thyrotoxicosis in the neonatal period is often caused by TSAb passing the placental barrier. We wanted to evaluate measurement of TSAb levels as a possible predictor of neonatal thyrotoxicosis in pregnant patients with Graves' disease. We retrospectively evaluated 18 consecutive pregnant patients with Graves' disease. In 16 patients TSAb were measured in early pregnancy, six had increased values. In 14 of 18 patients normal values were found in late pregnancy and none of the children developed neonatal thyrotoxicosis. Two patients had greatly elevated TSAb values, and their children had neonatal thyrotoxicosis. Two patients had slightly elevated TSAb levels and delivered normal children. We conclude that all pregnant patients with an actual or a history of Graves' disease, should have measured TSAb. High TSAb values in late pregnancy indicate a considerable risk of neonatal thyrotoxicosis.
pubmed:language
dan
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Feb
pubmed:issn
0041-5782
pubmed:author
pubmed:issnType
Print
pubmed:day
17
pubmed:volume
159
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
1086-9
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
1997
pubmed:articleTitle
[Thyroid stimulating antibodies in pregnant women with Graves' disease and neonatal thyrotoxicosis].
pubmed:affiliation
Medicinsk endokrinologisk afdeling F. Amtssygehuset i Herlev.
pubmed:publicationType
Journal Article, English Abstract, Case Reports, Research Support, Non-U.S. Gov't