Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
5
pubmed:dateCreated
1997-4-8
pubmed:abstractText
We sought to determine how often angiotensin-converting enzyme (ACE) inhibitors are prescribed as a discharge medication among eligible patients > or = 65 years old with an acute myocardial infarction; to identify patient characteristics associated with the decision to prescribe ACE inhibitors; and to determine the factors associated with the decision to obtain an evaluation of left ventricular function among patients who have no contraindications to ACE inhibitors. We addressed these aims with an observational study of consecutive elderly Medicare beneficiary survivors of an acute myocardial infarction hospitalized in Alabama, Connecticut, Iowa, and Wisconsin between June 1992 and February 1993. Among the 5,453 patients without a contraindication to ACE inhibitors at discharge, 3,528 (65%) had an evaluation of left ventricular function. Of the 1,228 patients without a contraindication to ACE inhibitors who had a left ventricular ejection fraction < or = 40%, 548 (45%) were prescribed the medication at discharge. In a multivariable analysis, an increased prescribed use of ACE inhibitors at discharge was correlated with several factors, including diabetes mellitus, congestive heart failure, ventricular tachycardia, and loop diuretics as a discharge medication. Patients admitted after the publication of the Survival and Ventricular Enlargement (SAVE) trial were significantly more likely to receive ACE inhibitors, although the absolute improvement in utilization was small in the 6 months after the trial results were published. In conclusion, improving the identification of appropriate patients for ACE inhibitors and increasing the prescription of ACE inhibitors for ideal patients may provide an excellent opportunity to improve care.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
AIM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Mar
pubmed:issn
0002-9149
pubmed:author
pubmed:issnType
Print
pubmed:day
1
pubmed:volume
79
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
581-6
pubmed:dateRevised
2008-11-21
pubmed:meshHeading
pubmed-meshheading:9068512-Aged, pubmed-meshheading:9068512-Aged, 80 and over, pubmed-meshheading:9068512-Alabama, pubmed-meshheading:9068512-Angiotensin-Converting Enzyme Inhibitors, pubmed-meshheading:9068512-Connecticut, pubmed-meshheading:9068512-Controlled Clinical Trials as Topic, pubmed-meshheading:9068512-Decision Making, pubmed-meshheading:9068512-Diabetes Complications, pubmed-meshheading:9068512-Diuretics, pubmed-meshheading:9068512-Drug Prescriptions, pubmed-meshheading:9068512-Drug Utilization, pubmed-meshheading:9068512-Female, pubmed-meshheading:9068512-Follow-Up Studies, pubmed-meshheading:9068512-Heart Failure, pubmed-meshheading:9068512-Hospitalization, pubmed-meshheading:9068512-Humans, pubmed-meshheading:9068512-Iowa, pubmed-meshheading:9068512-Male, pubmed-meshheading:9068512-Medicaid, pubmed-meshheading:9068512-Multivariate Analysis, pubmed-meshheading:9068512-Myocardial Infarction, pubmed-meshheading:9068512-Patient Discharge, pubmed-meshheading:9068512-Retrospective Studies, pubmed-meshheading:9068512-Stroke Volume, pubmed-meshheading:9068512-Tachycardia, Ventricular, pubmed-meshheading:9068512-United States, pubmed-meshheading:9068512-Ventricular Function, Left, pubmed-meshheading:9068512-Wisconsin
pubmed:year
1997
pubmed:articleTitle
Determinants of appropriate use of angiotensin-converting enzyme inhibitors after acute myocardial infarction in persons > or = 65 years of age.
pubmed:affiliation
Department of Medicine, Yale School of Medicine, New Haven, Connecticut 06520-8017, USA.
pubmed:publicationType
Journal Article