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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
1
|
pubmed:dateCreated |
1997-3-20
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pubmed:abstractText |
We have examined in eight male volunteers the effect of midazolam sedation on the relationship between timing of spontaneous ventilations and heart beat. On 2 study days, subjects received either midazolam 0.1 mg kg-1 or saline placebo while recordings were made of ECG and ventilatory impedance pneumography. We observed in all midazolam-treated subjects clear evidence of synchronous or non-synchronous coupling between ventilation and heart beat. Non-synchronous coupling was seen in two placebo-treated subjects, one of whom had slept during the recording period. We conclude that cardioventilatory coupling is a major determinant of ventilatory timing in sedated subjects.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Jan
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pubmed:issn |
0007-0912
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pubmed:author | |
pubmed:issnType |
Print
|
pubmed:volume |
78
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
100-1
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pubmed:dateRevised |
2004-11-17
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pubmed:meshHeading |
pubmed-meshheading:9059217-Adult,
pubmed-meshheading:9059217-Electrocardiography,
pubmed-meshheading:9059217-Heart Rate,
pubmed-meshheading:9059217-Humans,
pubmed-meshheading:9059217-Hypnotics and Sedatives,
pubmed-meshheading:9059217-Male,
pubmed-meshheading:9059217-Midazolam,
pubmed-meshheading:9059217-Periodicity,
pubmed-meshheading:9059217-Respiration
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pubmed:year |
1997
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pubmed:articleTitle |
Coupling of spontaneous ventilation to heart beat during benzodiazepine sedation.
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pubmed:affiliation |
Wellington School of Medicine, New Zealand.
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pubmed:publicationType |
Journal Article,
Clinical Trial,
Randomized Controlled Trial
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