Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
1
pubmed:dateCreated
1997-3-20
pubmed:abstractText
We have examined in eight male volunteers the effect of midazolam sedation on the relationship between timing of spontaneous ventilations and heart beat. On 2 study days, subjects received either midazolam 0.1 mg kg-1 or saline placebo while recordings were made of ECG and ventilatory impedance pneumography. We observed in all midazolam-treated subjects clear evidence of synchronous or non-synchronous coupling between ventilation and heart beat. Non-synchronous coupling was seen in two placebo-treated subjects, one of whom had slept during the recording period. We conclude that cardioventilatory coupling is a major determinant of ventilatory timing in sedated subjects.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Jan
pubmed:issn
0007-0912
pubmed:author
pubmed:issnType
Print
pubmed:volume
78
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
100-1
pubmed:dateRevised
2004-11-17
pubmed:meshHeading
pubmed:year
1997
pubmed:articleTitle
Coupling of spontaneous ventilation to heart beat during benzodiazepine sedation.
pubmed:affiliation
Wellington School of Medicine, New Zealand.
pubmed:publicationType
Journal Article, Clinical Trial, Randomized Controlled Trial