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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
2
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pubmed:dateCreated |
1997-4-7
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pubmed:databankReference |
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pubmed:abstractText |
We have cloned and sequenced the p53-encoding rabbit cDNA (Oryctolagus cuniculus). The encoded product is 86% and 80% homologous to human and mouse p53, respectively. It features many characteristics found in all p53 proteins: (i) the five domains highly conserved during evolution, (ii) an acidic N terminus, (iii) a hydrophilic C terminus and (iv) a penultimate serine residue. Immunoprecipitation of the cDNA-encoded protein by monoclonal antibodies specific for mammalian p53 has confirmed the identity of the protein.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Feb
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pubmed:issn |
0378-1119
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:day |
7
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pubmed:volume |
185
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
169-73
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:9055811-Amino Acid Sequence,
pubmed-meshheading:9055811-Animals,
pubmed-meshheading:9055811-Base Sequence,
pubmed-meshheading:9055811-Cloning, Molecular,
pubmed-meshheading:9055811-Cross Reactions,
pubmed-meshheading:9055811-DNA, Complementary,
pubmed-meshheading:9055811-Humans,
pubmed-meshheading:9055811-Mice,
pubmed-meshheading:9055811-Molecular Sequence Data,
pubmed-meshheading:9055811-Precipitin Tests,
pubmed-meshheading:9055811-Rabbits,
pubmed-meshheading:9055811-Sequence Analysis, DNA,
pubmed-meshheading:9055811-Sequence Homology, Amino Acid,
pubmed-meshheading:9055811-Tumor Suppressor Protein p53
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pubmed:year |
1997
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pubmed:articleTitle |
cDNA cloning and immunological characterization of rabbit p53.
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pubmed:affiliation |
U64 INSERM, Hôpital Tenon, Paris, France.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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