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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
4
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pubmed:dateCreated |
1997-3-20
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pubmed:databankReference |
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pubmed:abstractText |
Protein antigens are presented to cytotoxic T lymphocytes as small peptides (approximately 9-10 amino acids long) bound to class I molecules of the major histocompatibility complex. The identification of tumor-associated antigens and specific peptide epitopes (i.e., antigenic determinants) may be useful in the development of anticancer vaccines. The generation of a cytotoxic T-cell response to one peptide epitope (amino acids 146-154) of human prostate-specific antigen (PSA) has been reported.
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pubmed:commentsCorrections |
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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|
pubmed:chemical |
|
|
pubmed:status |
MEDLINE
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pubmed:month |
Feb
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pubmed:issn |
0027-8874
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pubmed:author |
|
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pubmed:issnType |
Print
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pubmed:day |
19
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pubmed:volume |
89
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
293-300
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pubmed:dateRevised |
2007-11-15
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pubmed:meshHeading |
pubmed-meshheading:9048833-Cell Line,
pubmed-meshheading:9048833-Colorectal Neoplasms,
pubmed-meshheading:9048833-Epitopes,
pubmed-meshheading:9048833-Flow Cytometry,
pubmed-meshheading:9048833-HLA-A2 Antigen,
pubmed-meshheading:9048833-Humans,
pubmed-meshheading:9048833-Leukemia, Myelogenous, Chronic, BCR-ABL Positive,
pubmed-meshheading:9048833-Male,
pubmed-meshheading:9048833-Molecular Sequence Data,
pubmed-meshheading:9048833-Neoplasm Proteins,
pubmed-meshheading:9048833-Prostate-Specific Antigen,
pubmed-meshheading:9048833-Prostatic Neoplasms,
pubmed-meshheading:9048833-Protein Binding,
pubmed-meshheading:9048833-T-Lymphocytes, Cytotoxic,
pubmed-meshheading:9048833-Tumor Cells, Cultured,
pubmed-meshheading:9048833-Vaccinia virus
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pubmed:year |
1997
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pubmed:articleTitle |
In vitro generation of human cytotoxic T lymphocytes specific for peptides derived from prostate-specific antigen.
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pubmed:affiliation |
Laboratory of Tumor Immunology and Biology, National Cancer Institute, National Institutes of Health, Bethesda, MD 20892-1750, USA.
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pubmed:publicationType |
Journal Article,
In Vitro
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