Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
5
pubmed:dateCreated
1997-4-4
pubmed:abstractText
Nuclear Microscopy, the extraction of analytical information from microscopic regions of a sample using a scanning focused high energy ion beam, has been increasing in popularity recently, despite its technical complexity. The three ion beam related techniques Particle Induced X-ray Emission (PIXE), Rutherford Backscattering Spectrometry (RBS) and Scanning Transmission Ion Microscopy (STIM) can be carried out simultaneously at sub-micron spatial resolutions, and provide structural and quantitative elemental analysis down to the parts per million levels of analytical sensitivity. These techniques are extremely useful for measuring any imbalances in trace elements, including metal ions, in localised regions of biological tissue, and as such can provide unique information on many diseases. In this paper we briefly describe the nuclear microscope and its related ion beam techniques, and briefly review recent work carried out using the nuclear microscope into the degenerative diseases Alzheimer's disease, Parkinson's disease and atherosclerosis.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:month
Oct
pubmed:issn
0037-5675
pubmed:author
pubmed:issnType
Print
pubmed:volume
37
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
527-31
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
1996
pubmed:articleTitle
A review of nuclear microscopy and applications in medicine.
pubmed:affiliation
Department of Physics, National University of Singapore, Singapore.
pubmed:publicationType
Journal Article, Review, Research Support, Non-U.S. Gov't