Linked Life Data

902831

Source:http://linkedlifedata.com/resource/pubmed/id/902831

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
4
pubmed:dateCreated
1977-11-25
pubmed:abstractText
The morphologic differences of two melanoma cell cultures from a primary melanoma and a metastasis are described. Though both cultures looked very similar at the beginning, they developed into totally different forms. Long, thin spindle-shaped cells containing an optically dense plasma grew in the cultured from the primary melanoma during its whole life span and the epithelioid cells of metastasis culture separated itself into different subcultures. The cells of both subcultures detached from the bottom of the culture flasks after 15 days of growth and began to spread again 7 days later with two very different forms. This transformation was observed three more times at monthly intervals. The possible relationship between these morphological alterations and the ability of the melanoma cells to produce metastases as well as the usefulness of melanoma cell cultures for immunodiagnostic purposes are discussed.
pubmed:language
ger
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:issn
0011-9075
pubmed:author
pubmed:issnType
Print
pubmed:volume
155
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
210-7
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
1977
pubmed:articleTitle
[Different behavior of human melanoma cells from primary tumor and metastases in vitro].
pubmed:publicationType
Journal Article, Comparative Study, English Abstract