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| Predicate | Object |
|---|---|
| rdf:type | |
| lifeskim:mentions | |
| pubmed:issue |
6
|
| pubmed:dateCreated |
1997-4-10
|
| pubmed:abstractText |
We describe brain stem auditory evoked potentials (BAEP) obtained in 48 full-term newborns (20 boys, 28 girls) presenting with high serum total bilirubin concentration (from 238 to 442 mM) without Rhesus of group A, B, O factors incompatibility. Recordings were performed on the 3rd day of life and repeated 5-7 days post-appropriate therapy with photostimulation and exchange transfusion (when bilirubin concentration had decreased below 136 mM). Supplementary recordings were performed 3, 6 and 12 weeks later in order to assess test-retest reliability of components. Mean values of BAEP latencies were compared with those obtained in 40 age-matched control subjects using the same recording procedures. At first recording session (on the 3rd day), latencies of waves III and V obtained in hyperbilirubinemic patients were significantly increased as compared with records in control subjects. Recordings performed 5 to 7 days post-therapy and during subsequent recording sessions showed no significant differences between patients and control groups. Serial neuropsychological evaluations obtained over a 3-year follow-up showed no subsequent neurodevelopmental abnormality for all patients. These findings suggest that hyperbilirubinemia can alter central neurotransmission in auditory brain stem pathways, but this modification is only transient.
|
| pubmed:language |
eng
|
| pubmed:journal | |
| pubmed:citationSubset |
IM
|
| pubmed:status |
MEDLINE
|
| pubmed:issn |
0987-7053
|
| pubmed:author | |
| pubmed:issnType |
Print
|
| pubmed:volume |
26
|
| pubmed:owner |
NLM
|
| pubmed:authorsComplete |
Y
|
| pubmed:pagination |
363-8
|
| pubmed:dateRevised |
2007-11-15
|
| pubmed:meshHeading |
pubmed-meshheading:9018698-Case-Control Studies,
pubmed-meshheading:9018698-Evaluation Studies as Topic,
pubmed-meshheading:9018698-Evoked Potentials, Auditory, Brain Stem,
pubmed-meshheading:9018698-Female,
pubmed-meshheading:9018698-Follow-Up Studies,
pubmed-meshheading:9018698-Humans,
pubmed-meshheading:9018698-Infant, Newborn,
pubmed-meshheading:9018698-Jaundice, Neonatal,
pubmed-meshheading:9018698-Male,
pubmed-meshheading:9018698-Neuropsychological Tests,
pubmed-meshheading:9018698-Reaction Time
|
| pubmed:year |
1996
|
| pubmed:articleTitle |
Newborns with hyperbilirubinemia: usefulness of brain stem auditory response evaluation.
|
| pubmed:affiliation |
Department of Neonatology, University of Chieti, Italy.
|
| pubmed:publicationType |
Journal Article
|