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rdf:type |
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lifeskim:mentions |
umls-concept:C0017337,
umls-concept:C0030844,
umls-concept:C0446013,
umls-concept:C0679058,
umls-concept:C0750502,
umls-concept:C1334043,
umls-concept:C1513380,
umls-concept:C1547699,
umls-concept:C1564871,
umls-concept:C2697616,
umls-concept:C2700640
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pubmed:issue |
1
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pubmed:dateCreated |
1997-2-27
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pubmed:databankReference |
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pubmed:abstractText |
Employing a PCR-aided strategy, a Penicillium chrysogenum gene (sreP) encoding a putative GATA-transcription factor has been cloned and characterized. Comparison of the genomic and cDNA sequences revealed the presence of an open reading frame (ORF) encoding a protein of 532 amino acids (aa) which is interrupted by two introns. The deduced aa sequence of sreP reveals 50% identity to a regulator of siderophore biosynthesis (URBS1) from Ustilago maydis over a stretch of 200 aa containing two GATA-type zinc finger motifs and a Cys-rich intervening sequence. Northern blot analysis indicated two transcripts of 2.2 and 2.7 kb in approximately equivalent amount. due to two major transcription start sites.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Jan
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pubmed:issn |
0378-1119
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:day |
3
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pubmed:volume |
184
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
33-7
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:9016950-Amino Acid Sequence,
pubmed-meshheading:9016950-Base Sequence,
pubmed-meshheading:9016950-Blotting, Northern,
pubmed-meshheading:9016950-CCAAT-Enhancer-Binding Proteins,
pubmed-meshheading:9016950-Cloning, Molecular,
pubmed-meshheading:9016950-DNA-Binding Proteins,
pubmed-meshheading:9016950-Fungal Proteins,
pubmed-meshheading:9016950-Gene Expression Regulation, Fungal,
pubmed-meshheading:9016950-Genes, Fungal,
pubmed-meshheading:9016950-Molecular Sequence Data,
pubmed-meshheading:9016950-Nuclear Proteins,
pubmed-meshheading:9016950-Penicillium chrysogenum,
pubmed-meshheading:9016950-Polymerase Chain Reaction,
pubmed-meshheading:9016950-Sequence Analysis,
pubmed-meshheading:9016950-Sequence Homology, Amino Acid,
pubmed-meshheading:9016950-Sterol Regulatory Element Binding Protein 1,
pubmed-meshheading:9016950-Transcription Factors,
pubmed-meshheading:9016950-Ustilago,
pubmed-meshheading:9016950-Zinc Fingers
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pubmed:year |
1997
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pubmed:articleTitle |
Molecular analysis of a Penicillium chrysogenum GATA factor encoding gene (sreP) exhibiting significant homology to the Ustilago maydis urbs1 gene.
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pubmed:affiliation |
Institut für Mikrobiologie (Medizinische Fakultät), Universität Innsbruck, Austria. hubertus.haas@uibk.ac.at
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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