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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
1
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pubmed:dateCreated |
1997-2-20
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pubmed:abstractText |
A single intron of 87 bp, close to the region encoding the C-terminal part of the signal peptide, was found in the gene of the 'short' scorpion toxin kaliotoxin 2 of Androctonus australis acting on various types of K+ channels. Its A+T content was particularly high (up to 86%). By walking and ligation-mediated PCR, the promoter sequences of the kaliotoxin 2 gene of Androctonus australis were studied. The transcription unit of the gene is 390 bp long. Consensus sequences were identified. The genes of 'short' scorpion toxins active on K+ channels are organized similarly to those of the 'long' scorpion toxins active on Na+ channels and not like those of structurally related insect defensins, which are intronless.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Jan
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pubmed:issn |
0014-5793
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:day |
27
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pubmed:volume |
402
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
45-9
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pubmed:dateRevised |
2008-11-21
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pubmed:meshHeading |
pubmed-meshheading:9013856-Amino Acid Sequence,
pubmed-meshheading:9013856-Animals,
pubmed-meshheading:9013856-Base Composition,
pubmed-meshheading:9013856-Base Sequence,
pubmed-meshheading:9013856-Consensus Sequence,
pubmed-meshheading:9013856-DNA, Complementary,
pubmed-meshheading:9013856-Introns,
pubmed-meshheading:9013856-Molecular Sequence Data,
pubmed-meshheading:9013856-Polymerase Chain Reaction,
pubmed-meshheading:9013856-Potassium Channels,
pubmed-meshheading:9013856-Promoter Regions, Genetic,
pubmed-meshheading:9013856-Protein Precursors,
pubmed-meshheading:9013856-Scorpion Venoms,
pubmed-meshheading:9013856-Scorpions
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pubmed:year |
1997
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pubmed:articleTitle |
Genomic organization of the KTX2 gene, encoding a 'short' scorpion toxin active on K+ channels.
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pubmed:affiliation |
Laboratoire de Biochimie, Faculté de Médecine Nord, Université de laMéditerranée, Marseille, France.
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pubmed:publicationType |
Journal Article
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