Linked Life Data

9000442

Source:http://linkedlifedata.com/resource/pubmed/id/9000442

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
1
pubmed:dateCreated
1997-2-28
pubmed:abstractText
Motor-evoked potentials elicited from transcranial magnetic stimulation were recorded from both cranial tibial muscles of 10 Lewis rats. One sciatic nerve was then transected and surgically reanastomosed and allowed to regenerate for 6 weeks. Walking function was tested weekly using a footprint test giving a functional sciatic nerve index. At the end of the study motor-evoked potentials were again performed, as were nerve conduction velocities and supramaximal stimulation of operated and unoperated sciatic nerves. The nerve was evaluated for myelinated axon numbers. Functional sciatic index, numbers of myelinated axons, nerve conduction velocities, and supramaximal stimulation demonstrated the regenerated nerve to be functional, but to a lesser extent than the unoperated nerve. In all cases the amplitude of the compound muscle action potential evoked from transcranial magnetic stimulation of the motor cortex was greater in the operated motor pathway. This finding demonstrates hyperexcitability of the motor pathway to magnetic stimulation during peripheral nerve regeneration.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:month
Jan
pubmed:issn
0014-4886
pubmed:author
pubmed:issnType
Print
pubmed:volume
143
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
18-24
pubmed:dateRevised
2003-11-14
pubmed:meshHeading
pubmed:year
1997
pubmed:articleTitle
Partial regeneration of the sciatic nerve in rats enhances motor excitability to magnetic stimulation.
pubmed:affiliation
Tufts University School of Veterinary Medicine, North Grafton, Massachusetts 01536, USA.
pubmed:publicationType
Journal Article