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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
1
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pubmed:dateCreated |
1997-5-2
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pubmed:abstractText |
Cancer in the oldest old is a novel problem, due to the recent burgeoning of the population aged 85 and older. This article addresses three critical questions related to cancer in the oldest old: Does the incidence of cancer increase after age 95? Is cancer a common cause of death for the oldest old? Is cancer accurately diagnosed in the oldest old? The authors analyzed a group of 507 autopsies of elderly, divided in three age groups, 75 90 years, 95 99, and over 99 (centenarians). The prevalence of cancer was 35% among the younger persons and 20% and 16% respectively for those aged 95 99 and for the centenarians. A fourth of the patients in the younger group died from cancer but only 9.5% of the people between 95 and 98 years and 7.1% of the centenarians died from cancer. The cancer was the direct cause of death for 67% of the younger persons and 41% of patients belonging to the two oldest groups. The prevalence of metastases was 63% for tumors occurring in persons aged 75 90, 32% in persons aged 95 98, and 29% in the centenarians. Cancer had been accurately diagnosed prior to death in 67.4% of persons aged 75 90, in 38.5% of those aged 95 99, and 29.4% of the centenarian. Cancer as cause of death had been underestimated in 16% of the cases in the younger persons and in almost 50% of cases of the oldest old. This study suggests that the incidence of cancer and the importance of cancer as a cause of death may decline after age 95 and that the clinical diagnoses underestimate significantly both the incidence of cancer and the prevalence of cancer deaths in the oldest old.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:status |
MEDLINE
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pubmed:month |
Feb
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pubmed:issn |
0749-0690
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
13
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
55-68
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:8995100-Age Distribution,
pubmed-meshheading:8995100-Aged,
pubmed-meshheading:8995100-Aged, 80 and over,
pubmed-meshheading:8995100-Autopsy,
pubmed-meshheading:8995100-Bias (Epidemiology),
pubmed-meshheading:8995100-Cause of Death,
pubmed-meshheading:8995100-Death Certificates,
pubmed-meshheading:8995100-Female,
pubmed-meshheading:8995100-Humans,
pubmed-meshheading:8995100-Incidence,
pubmed-meshheading:8995100-Italy,
pubmed-meshheading:8995100-Male,
pubmed-meshheading:8995100-Neoplasms,
pubmed-meshheading:8995100-Prevalence
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pubmed:year |
1997
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pubmed:articleTitle |
Cancer of the oldest old. What we have learned from autopsy studies.
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pubmed:affiliation |
Department of Pathology, University of Trieste, Trieste, Italy.
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pubmed:publicationType |
Journal Article,
Comparative Study,
Review
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