Linked Life Data

8981071

Source:http://linkedlifedata.com/resource/pubmed/id/8981071

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
7
pubmed:dateCreated
1997-4-1
pubmed:abstractText
1. Efficiency of preventive and reversive insulin therapy was compared on rat myocardium following streptozotocin treatment to study the reversibility of diabetic catecholamine resistance. 2. When insulin substitution was initiated immediately after streptozotocin treatment, insulin successfully prevented the development of diabetic catecholamine resistance of the myocardium. 3. When insulin substitution was initiated following the development of isoproterenol resistance, insulin failed to restore physiological catecholamine sensitivity. 4. These results indicate that once diabetic alterations have already developed, recovery of biological functions to normal by exogenous insulin substitution might be ineffective.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Oct
pubmed:issn
0306-3623
pubmed:author
pubmed:issnType
Print
pubmed:volume
27
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
1219-22
pubmed:dateRevised
2011-11-17
pubmed:meshHeading
pubmed:year
1996
pubmed:articleTitle
Insulin reversibility of the isoproterenol resistance of diabetic rat myocardium.
pubmed:affiliation
Department of Physiology, University Medical School of Debrecen, Hungary. tom@phys.dote.hu
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't