8970490

Source:http://linkedlifedata.com/resource/pubmed/id/8970490

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Predicate	Object
rdf:type	pubmed:Citation
lifeskim:mentions	umls-concept:C0033137, umls-concept:C0242485, umls-concept:C0348026, umls-concept:C0871470, umls-concept:C0918012, umls-concept:C1522609, umls-concept:C1554112
pubmed:issue	12
pubmed:dateCreated	1997-1-13
pubmed:abstractText	We investigated the value of the ankle-brachial systolic pressure index (ABPI) as a test for the diagnosis of peripheral arterial occlusive disease (PAOD) in general practice. ABPI measurements on 231 legs of 117 subjects performed in three general practice centers (GPC) were compared with the diagnostic conclusions of a Vascular Laboratory. The optimum cutoff value for the ABPI, its accuracy and diagnostic value were estimated. In a subpopulation of 51 subjects for whom repeated measurements were available, we checked whether taking the mean of three consecutive ABPIs for test outcome would enhance diagnostic performance. Receiver Operating Characteristic analysis showed that overall performance of the GPC ABPI was good (area under the curve approximately 0.9). Performing repeated ABPI measurements was superior to performing a single measurement. The optimum cutoff value for the ABPI was 0.97, associated with a diagnostic odds ratio (OR) of 17 and an accuracy of 81%. In a somewhat more selected subpopulation, the optimum cutoff value was 0.92 (OR 70, accuracy 90%). On the basis of our results, we suggest the following rule of thumb: if the ABPI < 0.8 or if the mean of three ABPIs < 0.9, it is highly probable that PAOD is present (PV+ > or = 95%); if the ABPI > 1.1 or if the mean of three ABPIs > 1.0, PAOD can be ruled out (PV- > or = 99%). In conclusion, in primary health care, the ABPI measurement can be a useful supplementary test in ambiguous diagnostic situations with regard to PAOD.
pubmed:language	eng
pubmed:journal	http://linkedlifedata.com/resource/pubmed/journal/8801383
pubmed:citationSubset	IM
pubmed:status	MEDLINE
pubmed:month	Dec
pubmed:issn	0895-4356
pubmed:author	pubmed-author:KaiserVV, pubmed-author:KesterA DAD, pubmed-author:KitslaarP JPJ, pubmed-author:KnottnerusJ AJA, pubmed-author:RinkensP EPE, pubmed-author:StoffersH EHE
pubmed:issnType	Print
pubmed:volume	49
pubmed:owner	NLM
pubmed:authorsComplete	Y
pubmed:pagination	1401-5
pubmed:dateRevised	2006-11-15
pubmed:meshHeading	pubmed-meshheading:8970490-Adult, pubmed-meshheading:8970490-Aged, pubmed-meshheading:8970490-Aged, 80 and over, pubmed-meshheading:8970490-Ankle, pubmed-meshheading:8970490-Arm, pubmed-meshheading:8970490-Arterial Occlusive Diseases, pubmed-meshheading:8970490-Blood Pressure, pubmed-meshheading:8970490-Blood Pressure Determination, pubmed-meshheading:8970490-Brachial Artery, pubmed-meshheading:8970490-Female, pubmed-meshheading:8970490-Humans, pubmed-meshheading:8970490-Laser-Doppler Flowmetry, pubmed-meshheading:8970490-Male, pubmed-meshheading:8970490-Middle Aged, pubmed-meshheading:8970490-Odds Ratio, pubmed-meshheading:8970490-Predictive Value of Tests, pubmed-meshheading:8970490-Primary Health Care, pubmed-meshheading:8970490-ROC Curve, pubmed-meshheading:8970490-Reproducibility of Results, pubmed-meshheading:8970490-Systole
pubmed:year	1996
pubmed:articleTitle	The diagnostic value of the measurement of the ankle-brachial systolic pressure index in primary health care.
pubmed:affiliation	Department of General Practice, University of Limburg, Maastricht, The Netherlands.
pubmed:publicationType	Journal Article, Research Support, Non-U.S. Gov't, Multicenter Study