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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
6
|
pubmed:dateCreated |
1996-12-3
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pubmed:abstractText |
To study the possibilities of genetic exchange between Vibrio cholerae of O1 and non-O1 serogroups, donor and recipient strains were developed. It was shown that toxicogenic strains of V. cholerae non-O1 appeared in vitro and in vivo as the result of conjugative transfer of rfb-NAG genes from avirulent V. cholerae non-O1 strains to toxicogenic strains belonging to V. cholerae O1 classical and eltor biovars. These genes are responsible for synthesis of O antigen of non-O1 serotype. It was established that foreign rfb-NAG genes have no effect on virulence properties of a causative agent of cholera. Apparently, pathogenic V. cholerae non-O1 strains with cholera toxin genes are generated due to transfer of rfb-NAG genes under natural conditions.
|
pubmed:language |
rus
|
pubmed:journal | |
pubmed:citationSubset |
IM
|
pubmed:chemical | |
pubmed:status |
MEDLINE
|
pubmed:month |
Jun
|
pubmed:issn |
0016-6758
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
32
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
744-9
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading | |
pubmed:year |
1996
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pubmed:articleTitle |
[Emergence of toxigenic Vibrio cholerae strains on non-O1 serotype as a result of the exchange of genetic information].
|
pubmed:publicationType |
Journal Article,
English Abstract
|