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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
3
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pubmed:dateCreated |
1977-10-20
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pubmed:abstractText |
Irradiation of the pigmented rabbit iris with a moderately low dose of argon laser light (5 applications of 750 mW, 500 micron, 0.5 sec) caused an immediate ocular response consisting of miosis, a rise of intra-ocular pressure and is accompanied by a disruption of the blood-aqueous barrier. Prostaglandin-like material was present in the aqueous humour withdrawn 60 minutes after irradiation. Prior treatment with indomethacin intravenously (20 mg/kg) or benoxinate topically (Novesine; 0.4%) greatly reduced the response and the combined use of the two drugs virtually abolished the ocular changes.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:issn |
0030-3755
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
175
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
153-8
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pubmed:dateRevised |
2007-9-17
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pubmed:meshHeading |
pubmed-meshheading:896143-Administration, Topical,
pubmed-meshheading:896143-Anesthetics, Local,
pubmed-meshheading:896143-Animals,
pubmed-meshheading:896143-Aqueous Humor,
pubmed-meshheading:896143-Fluorescein Angiography,
pubmed-meshheading:896143-Indomethacin,
pubmed-meshheading:896143-Injections, Intravenous,
pubmed-meshheading:896143-Intraocular Pressure,
pubmed-meshheading:896143-Iris,
pubmed-meshheading:896143-Iritis,
pubmed-meshheading:896143-Lasers,
pubmed-meshheading:896143-Prostaglandins,
pubmed-meshheading:896143-Rabbits
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pubmed:year |
1977
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pubmed:articleTitle |
Prostaglandin and nerve-mediated response of the rabbit eye to argon laser irradiation of the iris.
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pubmed:publicationType |
Journal Article
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