rdf:type |
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lifeskim:mentions |
umls-concept:C0006556,
umls-concept:C0009015,
umls-concept:C0021853,
umls-concept:C0026682,
umls-concept:C0034693,
umls-concept:C0034721,
umls-concept:C0162775,
umls-concept:C0178595,
umls-concept:C0597484,
umls-concept:C0598850,
umls-concept:C0728938
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pubmed:issue |
1-2
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pubmed:dateCreated |
1997-1-7
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pubmed:databankReference |
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pubmed:abstractText |
In this report we present the full-length cDNA and deduced 587 amino acid sequence of a putative rat intestinal Na+/dicarboxylate cotransporter. It shows sequence and structural similarity to a rabbit renal Na+/dicarboxylate cotransporter. An unexpected fining was the presence of a C-terminal transmembrane region that is homologous with an 87 amino acid hydrophobic region of a rat intestinal mucin, M2. Mucin-related sequences in transporter proteins have not been described before.
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pubmed:language |
eng
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pubmed:journal |
|
pubmed:citationSubset |
IM
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pubmed:chemical |
http://linkedlifedata.com/resource/pubmed/chemical/Carrier Proteins,
http://linkedlifedata.com/resource/pubmed/chemical/DNA, Complementary,
http://linkedlifedata.com/resource/pubmed/chemical/Dicarboxylic Acid Transporters,
http://linkedlifedata.com/resource/pubmed/chemical/Membrane Proteins,
http://linkedlifedata.com/resource/pubmed/chemical/Mucins,
http://linkedlifedata.com/resource/pubmed/chemical/Organic Anion Transporters...,
http://linkedlifedata.com/resource/pubmed/chemical/RNA, Messenger,
http://linkedlifedata.com/resource/pubmed/chemical/SLC13A2 protein, human,
http://linkedlifedata.com/resource/pubmed/chemical/Slc13a2 protein, rat,
http://linkedlifedata.com/resource/pubmed/chemical/Symporters
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pubmed:status |
MEDLINE
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pubmed:month |
Nov
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pubmed:issn |
0006-3002
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pubmed:author |
|
pubmed:issnType |
Print
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pubmed:day |
11
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pubmed:volume |
1309
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
58-62
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:8950177-Amino Acid Sequence,
pubmed-meshheading:8950177-Animals,
pubmed-meshheading:8950177-Base Sequence,
pubmed-meshheading:8950177-Carrier Proteins,
pubmed-meshheading:8950177-Cloning, Molecular,
pubmed-meshheading:8950177-DNA, Complementary,
pubmed-meshheading:8950177-Dicarboxylic Acid Transporters,
pubmed-meshheading:8950177-Intestines,
pubmed-meshheading:8950177-Membrane Proteins,
pubmed-meshheading:8950177-Molecular Sequence Data,
pubmed-meshheading:8950177-Mucins,
pubmed-meshheading:8950177-Organic Anion Transporters, Sodium-Dependent,
pubmed-meshheading:8950177-RNA, Messenger,
pubmed-meshheading:8950177-Rats,
pubmed-meshheading:8950177-Sequence Homology, Amino Acid,
pubmed-meshheading:8950177-Symporters
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pubmed:year |
1996
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pubmed:articleTitle |
Cloning of the cDNA for a rat intestinal Na+/dicarboxylate cotransporter reveals partial sequence homology with a rat intestinal mucin.
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pubmed:affiliation |
Division of Research Biochemistry, Hospital for Sick Children, Toronto, ON, Canada.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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