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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
2
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pubmed:dateCreated |
1997-3-3
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pubmed:abstractText |
HEMOCO is a multicenter prospective cohort set up in 1989 to monitor 407 French hemophiliacs infected by HIV-1 and recruited in 4 hemophilia treatment centers in the Paris region. As of 15 July 1995, 42% of the patients in the cohort had developed stage B HIV disease and 29% stage C disease (AIDS); 23.1% of the patients had died. The cumulative proportion of patients with AIDS was 4.5% at 5 years and 27.4% at 10 years, while the respective mortality rates were 3.8% and 19.5%. In our study, only age was predictive of AIDS, with an estimated relative risk of 1.2 per 10-year age increment; this factor was also predictive of death. After 10 years of follow-up, 6.1% of the study population had no clinical or laboratory signs of immunodepression. The follow-up protocol in the HEMOCO protocol is the same as that in the French SEROCO study, which includes men infected by HIV-1 through sexual contact. This will allow us to compare the progression of HIV infection between these two exposure groups.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:status |
MEDLINE
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pubmed:month |
Apr
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pubmed:issn |
1269-3286
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
38
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
193-8
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pubmed:dateRevised |
2004-11-17
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pubmed:meshHeading |
pubmed-meshheading:8932002-Acquired Immunodeficiency Syndrome,
pubmed-meshheading:8932002-Adolescent,
pubmed-meshheading:8932002-Adult,
pubmed-meshheading:8932002-Child,
pubmed-meshheading:8932002-Child, Preschool,
pubmed-meshheading:8932002-Cohort Studies,
pubmed-meshheading:8932002-Disease-Free Survival,
pubmed-meshheading:8932002-Enzyme-Linked Immunosorbent Assay,
pubmed-meshheading:8932002-France,
pubmed-meshheading:8932002-HIV Seropositivity,
pubmed-meshheading:8932002-HIV-1,
pubmed-meshheading:8932002-Hemophilia A,
pubmed-meshheading:8932002-Humans,
pubmed-meshheading:8932002-Infant,
pubmed-meshheading:8932002-Male,
pubmed-meshheading:8932002-Prospective Studies
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pubmed:year |
1996
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pubmed:articleTitle |
HEMOCO: a French prospective study of hemophiliacs infected by human immunodeficiency virus type 1 (HIV-1).
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pubmed:affiliation |
Unité INSERM U-292, Hôpital de Bicêtre, Le Kremlin-Bicêtre, France.
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pubmed:publicationType |
Journal Article
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