Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
4 ( Pt 1)
pubmed:dateCreated
1997-2-25
pubmed:abstractText
The aim of the present study was to examine xylitol metabolism by dental plaque collected immediately after the use of xylitol gum. Plaque was collected from 12 individuals immediately before and after xylitol exposure. The effect on xylitol metabolism by dental plaque of a 3 d discontinuation of the xylitol exposure was also examined. Xylitol metabolism by the plaque suspensions was initiated by adding [14C]xylitol and analyzed by HPLC. The results showed increased xylitol metabolism after 11 wk of chewing xylitol-containing gum. The ability to metabolize xylitol was rapidly reduced after the discontinuation of the xylitol exposure. It is suggested that an induction of enzymes in one or more of the species of plaque bacteria may have caused this effect. Glucose metabolism, which also was studied in the plaque samples, was decreased after xylitol exposure, but increased again 3 d after cessation of the xylitol exposure. It is suggested that the reduced glycolysis was caused by accumulation of intracellular xylitol-5-phosphate in some plaque bacteria during the xylitol exposure.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
D
pubmed:chemical
http://linkedlifedata.com/resource/pubmed/chemical/Acetates, http://linkedlifedata.com/resource/pubmed/chemical/Carbon Radioisotopes, http://linkedlifedata.com/resource/pubmed/chemical/Chewing Gum, http://linkedlifedata.com/resource/pubmed/chemical/Formates, http://linkedlifedata.com/resource/pubmed/chemical/Glucose, http://linkedlifedata.com/resource/pubmed/chemical/Lactates, http://linkedlifedata.com/resource/pubmed/chemical/Pentosephosphates, http://linkedlifedata.com/resource/pubmed/chemical/Propionates, http://linkedlifedata.com/resource/pubmed/chemical/Radiopharmaceuticals, http://linkedlifedata.com/resource/pubmed/chemical/Sucrose, http://linkedlifedata.com/resource/pubmed/chemical/Sweetening Agents, http://linkedlifedata.com/resource/pubmed/chemical/Xylitol, http://linkedlifedata.com/resource/pubmed/chemical/xylitol 5-phosphate
pubmed:status
MEDLINE
pubmed:month
Aug
pubmed:issn
0909-8836
pubmed:author
pubmed:issnType
Print
pubmed:volume
104
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
359-62
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed-meshheading:8930583-Acetates, pubmed-meshheading:8930583-Adult, pubmed-meshheading:8930583-Bacteria, pubmed-meshheading:8930583-Carbon Radioisotopes, pubmed-meshheading:8930583-Chewing Gum, pubmed-meshheading:8930583-Chromatography, High Pressure Liquid, pubmed-meshheading:8930583-Dental Plaque, pubmed-meshheading:8930583-Female, pubmed-meshheading:8930583-Fermentation, pubmed-meshheading:8930583-Formates, pubmed-meshheading:8930583-Glucose, pubmed-meshheading:8930583-Glycolysis, pubmed-meshheading:8930583-Humans, pubmed-meshheading:8930583-Lactates, pubmed-meshheading:8930583-Male, pubmed-meshheading:8930583-Pentosephosphates, pubmed-meshheading:8930583-Propionates, pubmed-meshheading:8930583-Radiopharmaceuticals, pubmed-meshheading:8930583-Sucrose, pubmed-meshheading:8930583-Sweetening Agents, pubmed-meshheading:8930583-Time Factors, pubmed-meshheading:8930583-Xylitol
pubmed:year
1996
pubmed:articleTitle
Xylitol fermentation by human dental plaque.
pubmed:affiliation
Department of Oral Biology, Faculty of Dentistry, University of Oslo, Norway. assev@ulrik.uio.no
pubmed:publicationType
Journal Article