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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
1
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pubmed:dateCreated |
1996-11-27
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pubmed:abstractText |
SNAP-25 is located on the plasma membrane and essential for exocytosis of neurotransmitters. It was suggested that SNAP-25 and syntaxin 1 via the interaction with VAMP-2 located on synaptic vesicles mediate the docking of the vesicles with the plasma membrane. In the present study, by means of biochemical and morphological analyses, we showed that SNAP-25 is present on chromaffin granules as well as on the plasma membrane. Reconstitution and immunoprecipitation analyses revealed that SNAP-25 on chromaffin granules has essentially the same properties as does SNAP-25 on the plasma membrane.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
http://linkedlifedata.com/resource/pubmed/chemical/Antibodies, Monoclonal,
http://linkedlifedata.com/resource/pubmed/chemical/Antigens, Surface,
http://linkedlifedata.com/resource/pubmed/chemical/Membrane Proteins,
http://linkedlifedata.com/resource/pubmed/chemical/Nerve Tissue Proteins,
http://linkedlifedata.com/resource/pubmed/chemical/R-SNARE Proteins,
http://linkedlifedata.com/resource/pubmed/chemical/SNARE Proteins,
http://linkedlifedata.com/resource/pubmed/chemical/Synaptosomal-Associated Protein 25,
http://linkedlifedata.com/resource/pubmed/chemical/Syntaxin 1,
http://linkedlifedata.com/resource/pubmed/chemical/Vesicular Transport Proteins
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pubmed:status |
MEDLINE
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pubmed:month |
Sep
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pubmed:issn |
0014-5793
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:day |
23
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pubmed:volume |
394
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
83-6
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:8925933-Animals,
pubmed-meshheading:8925933-Antibodies, Monoclonal,
pubmed-meshheading:8925933-Antigens, Surface,
pubmed-meshheading:8925933-Cattle,
pubmed-meshheading:8925933-Cell Fractionation,
pubmed-meshheading:8925933-Chromaffin Granules,
pubmed-meshheading:8925933-Exocytosis,
pubmed-meshheading:8925933-Immunoblotting,
pubmed-meshheading:8925933-Immunohistochemistry,
pubmed-meshheading:8925933-Membrane Proteins,
pubmed-meshheading:8925933-Microscopy, Electron,
pubmed-meshheading:8925933-Nerve Tissue Proteins,
pubmed-meshheading:8925933-Precipitin Tests,
pubmed-meshheading:8925933-R-SNARE Proteins,
pubmed-meshheading:8925933-SNARE Proteins,
pubmed-meshheading:8925933-Synaptosomal-Associated Protein 25,
pubmed-meshheading:8925933-Syntaxin 1,
pubmed-meshheading:8925933-Vesicular Transport Proteins
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pubmed:year |
1996
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pubmed:articleTitle |
SNAP-25 is present on chromaffin granules and acts as a SNAP receptor.
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pubmed:affiliation |
School of Life Science, Tokyo University of Pharmacy and Life Science, Japan.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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