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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
3
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pubmed:dateCreated |
1977-10-14
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pubmed:abstractText |
Acid secretion in Pavlov pouches in dogs is known to increase after antrectomy in response to histamine and gastrin. Dogs with gastric fistulae were tested with histamine and tetragastrin as a control study. The vagal nerve fibers to the antrum were divided and the dogs underwent repeat testing. Finally an antrectomy was performed and final dose-response data were collected. After antrectomy there was an increased acid response to histamine and tetragastrin. We postulate that the vagal fibers innervating the antrum are probably not a factor in this increase. Furthermore, we believe that the increased acid secretion after antrectomy observed in the dog and the decrease known to occur in the human being is a species difference and is not related to the pouch method of study used in earlier studies of the antrectomized dog.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
AIM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Sep
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pubmed:issn |
0016-5085
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
73
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
492-4
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:892347-Animals,
pubmed-meshheading:892347-Denervation,
pubmed-meshheading:892347-Dogs,
pubmed-meshheading:892347-Dose-Response Relationship, Drug,
pubmed-meshheading:892347-Duodenum,
pubmed-meshheading:892347-Gastric Fistula,
pubmed-meshheading:892347-Gastric Juice,
pubmed-meshheading:892347-Gastrins,
pubmed-meshheading:892347-Histamine,
pubmed-meshheading:892347-Humans,
pubmed-meshheading:892347-Pyloric Antrum,
pubmed-meshheading:892347-Species Specificity,
pubmed-meshheading:892347-Stimulation, Chemical,
pubmed-meshheading:892347-Vagotomy,
pubmed-meshheading:892347-Vagus Nerve
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pubmed:year |
1977
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pubmed:articleTitle |
Gastric acid secretion in gastric fistula dogs after antral denervation and antrectomy.
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pubmed:publicationType |
Journal Article,
Comparative Study
|