Linked Life Data

8921249

Source:http://linkedlifedata.com/resource/pubmed/id/8921249

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
8
pubmed:dateCreated
1997-2-6
pubmed:abstractText
It was shown previously that the spectral sensitivity of luminosity/H1-type horizontal cells (HCs) in carp retinae reflects the absorption spectrum of red-sensitive cones for long wavelengths but can appear highly variable and "truncated' in the short-wavelength region of the spectrum. We have found that light-adaptation sharpened the red-sensitive spectral peak and decreased the blue/red response amplitude ratio (B/R ratio), mainly by decreasing the response to short-wavelength stimuli. The adaptation effect was more pronounced for red background light than for blue. During dark adaptation, the B/R ratio increased steadily. Exogenous dopamine (DA; 5 microM) changed the spectral response profile in a similar way to light-adaptation. However, the effect of light-adaptation in reducing the B/R ratio was still seen in retinae bathed in 5 microM DA. This effect of background adaptation was also recorded in retinae bathed in 37 microM haloperidol, as well as in retinae pretreated with 6-hydroxydopamine (i.e. DA-depleted). The results suggest that (i) short-wavelength-sensitive cones play a dynamic role in determining the spectral response profile of H1 HCs and (ii) spectral response characteristics are modulated independently by exogenous DA and an unknown endogenous neuromodulator which is activated by light-adaptation.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Aug
pubmed:issn
0953-816X
pubmed:author
pubmed:issnType
Print
pubmed:volume
8
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
1571-9
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
1996
pubmed:articleTitle
Spectral plasticity of H1 horizontal cells in carp retina: independent modulation by dopamine and light-adaptation.
pubmed:affiliation
Department of Biology, Imperial College of Science, Technology and Medicine, London, UK.
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't