Linked Life Data

8903781

Source:http://linkedlifedata.com/resource/pubmed/id/8903781

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
1
pubmed:dateCreated
1997-2-13
pubmed:abstractText
Chloroquine diphosphate, a highly water-soluble drug, was encapsulated by using a non-solvent addition coarcevation method. The coating material employed was Eudragit RS100. The liquid manufacturing vehicle was tetrahydrofuran (THF) while the non-solvent liquid was cyclohexane. Polyisobutylene (PIB) was used as an anti-aggregating agent. Particle size as well as shape evaluation was performed. Total drug content, in vitro drug release (from the microcapsules) as well as tasting test experiments were performed. The release studies on the microcapsules revealed an in vitro prolonged release effect while at the same time the bitter taste of the drug appeared to have been considerably masked by this method.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:issn
0265-2048
pubmed:author
pubmed:issnType
Print
pubmed:volume
13
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
1-8
pubmed:dateRevised
2009-7-21
pubmed:meshHeading
pubmed:articleTitle
Microencapsulation of chloroquine diphosphate by Eudragit RS100.
pubmed:affiliation
School of Pharmacy, Muhimbili University College of Health Sciences, Dar-es-Salaam, Tanzania.
pubmed:publicationType
Journal Article