Switch to
| Predicate | Object |
|---|---|
| rdf:type | |
| lifeskim:mentions | |
| pubmed:issue |
4
|
| pubmed:dateCreated |
1996-12-11
|
| pubmed:abstractText |
Single-photon emission computed tomography (SPECT) and transcranial Doppler (TCD) ultrasonography were used to assess brain perfusion during cardiopulmonary bypass. Intravenous injections of technetium 99 m-hexamethylpropyleneamineoxime (99mTc-HMPAO) were administered before surgery and intraoperatively after the first 2 minutes in the first patient and at the end (42 minutes) of cardiopulmonary bypass in the second patient. The total middle cerebral artery territory counts were calculated using the region-of-interest method and compared to cerebellar regional counts. 99mTc-HMPAO uptake on SPECT scans was increased at the beginning and at the end of cardiopulmonary bypass, compared to baseline preoperative values (11-17%) in the presence of multiple microembolic signals on TCD (n1 = 35 and n2 = 42 for unilateral middle cerebral artery monitoring). These results indicate the feasibility of using HMPAO-SPECT to study brain perfusion changes during cardiac surgery. A combination of SPECT and TCD ultrasonography may be used to study the impact of microembolism during cardiac surgery with cardiopulmonary bypass.
|
| pubmed:language |
eng
|
| pubmed:journal | |
| pubmed:citationSubset |
IM
|
| pubmed:chemical | |
| pubmed:status |
MEDLINE
|
| pubmed:month |
Oct
|
| pubmed:issn |
1051-2284
|
| pubmed:author | |
| pubmed:issnType |
Print
|
| pubmed:volume |
6
|
| pubmed:owner |
NLM
|
| pubmed:authorsComplete |
Y
|
| pubmed:pagination |
243-5
|
| pubmed:dateRevised |
2006-11-15
|
| pubmed:meshHeading |
pubmed-meshheading:8903078-Brain,
pubmed-meshheading:8903078-Cardiac Surgical Procedures,
pubmed-meshheading:8903078-Cardiopulmonary Bypass,
pubmed-meshheading:8903078-Cerebellum,
pubmed-meshheading:8903078-Cerebral Arteries,
pubmed-meshheading:8903078-Cerebrovascular Circulation,
pubmed-meshheading:8903078-Echoencephalography,
pubmed-meshheading:8903078-Feasibility Studies,
pubmed-meshheading:8903078-Humans,
pubmed-meshheading:8903078-Intracranial Embolism and Thrombosis,
pubmed-meshheading:8903078-Monitoring, Intraoperative,
pubmed-meshheading:8903078-Organotechnetium Compounds,
pubmed-meshheading:8903078-Oximes,
pubmed-meshheading:8903078-Pilot Projects,
pubmed-meshheading:8903078-Technetium Tc 99m Exametazime,
pubmed-meshheading:8903078-Tomography, Emission-Computed, Single-Photon,
pubmed-meshheading:8903078-Ultrasonography, Doppler, Transcranial
|
| pubmed:year |
1996
|
| pubmed:articleTitle |
Feasibility of SPECT for studies of brain perfusion during cardiopulmonary bypass.
|
| pubmed:affiliation |
Department of Anesthesiology, Buffalo General Hospital, State University of New York, USA.
|
| pubmed:publicationType |
Journal Article,
Comparative Study
|