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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
3
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pubmed:dateCreated |
1996-11-27
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pubmed:abstractText |
The decarboxylated dimer of aminoethylcysteine ketimine has been investigated for a possible general protective effect against oxyradical damage. It has been found that the dimer protects brain microsomes against lipid peroxidation induced by NADPH in the presence of Fe(III)-ADP chelate or by cumene hydroperoxide. The compound also inhibits lipid peroxidation stimulated by L-dopa and related compounds in the presence of Fe(III)-ADP complex. Furthermore the dimer is able to protect deoxyribose against hydroxyl radical induced degradation. These observations suggest that the dimer is a lipid peroxidation protective agent and a free radical scavenger.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:issn |
0748-6642
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
27
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
223-9
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:8868582-Adenosine Diphosphate,
pubmed-meshheading:8868582-Amino Acids, Sulfur,
pubmed-meshheading:8868582-Animals,
pubmed-meshheading:8868582-Antioxidants,
pubmed-meshheading:8868582-Brain Chemistry,
pubmed-meshheading:8868582-Cattle,
pubmed-meshheading:8868582-Iron,
pubmed-meshheading:8868582-Levodopa,
pubmed-meshheading:8868582-Lipid Peroxidation,
pubmed-meshheading:8868582-Liposomes,
pubmed-meshheading:8868582-Microsomes,
pubmed-meshheading:8868582-NADP,
pubmed-meshheading:8868582-Oxidation-Reduction
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pubmed:year |
1995
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pubmed:articleTitle |
Antioxidant properties of the decarboxylated dimer of aminoethylcysteine ketimine.
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pubmed:affiliation |
Dipartimento di Scienze Biochimiche A. Rossi Fanelli, Università di Roma La Sapienza, Italy.
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pubmed:publicationType |
Journal Article,
In Vitro,
Research Support, Non-U.S. Gov't
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