Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
2
pubmed:dateCreated
1997-3-6
pubmed:abstractText
Many reports have shown a deleterious effect from the prolongation of radiation treatment duration on local control of squamous cell carcinomas in a variety of sites. To study whether a similar effect was found in adenocarcinoma of the rectum, a retrospective review was performed of 353 patients treated by external beam radiation therapy for primary adenocarcinoma of the rectum. At 4 years, the local control rate for mobile tumours was 25 percent; for fixed tumours it was 7 percent. By multiple Cox regression analysis, the only factor statistically significant for local control was tumour fixation (P=0.02). Neither treatment length (P=0.44), nor the presence of an interruption in treatment (P=0.41) was significant. The possible explanations for these observations are discussed.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:issn
0936-6555
pubmed:author
pubmed:issnType
Print
pubmed:volume
8
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
97-101
pubmed:dateRevised
2008-3-10
pubmed:meshHeading
pubmed-meshheading:8859606-Adenocarcinoma, pubmed-meshheading:8859606-Adult, pubmed-meshheading:8859606-Aged, pubmed-meshheading:8859606-Aged, 80 and over, pubmed-meshheading:8859606-Disease-Free Survival, pubmed-meshheading:8859606-Female, pubmed-meshheading:8859606-Follow-Up Studies, pubmed-meshheading:8859606-Humans, pubmed-meshheading:8859606-Male, pubmed-meshheading:8859606-Middle Aged, pubmed-meshheading:8859606-Neoplasm Recurrence, Local, pubmed-meshheading:8859606-Patient Care Planning, pubmed-meshheading:8859606-Prognosis, pubmed-meshheading:8859606-Radiotherapy Dosage, pubmed-meshheading:8859606-Rectal Neoplasms, pubmed-meshheading:8859606-Regression Analysis, pubmed-meshheading:8859606-Remission Induction, pubmed-meshheading:8859606-Retrospective Studies, pubmed-meshheading:8859606-Survival Rate, pubmed-meshheading:8859606-Time Factors
pubmed:year
1996
pubmed:articleTitle
The absence of an adverse effect of prolongation of radiation treatment of primary rectal adenocarcinoma.
pubmed:affiliation
Princess Margaret Hospital, Toronto, Ontario, Canada.
pubmed:publicationType
Journal Article