Linked Life Data

8858624

Source:http://linkedlifedata.com/resource/pubmed/id/8858624

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
2
pubmed:dateCreated
1996-12-30
pubmed:abstractText
Diffusion-weighted magnetic resonance imaging (MRI) was used to assess the effect of an astrocytic Na+2Cl-K+ cotransporter inhibitor, a novel torasemide derivative, on the time course and spatial evolution of a focal cerebral ischemia in the rat. The drug (1 mg/ kg, i.p.) was injected 30 min before middle cerebral artery occlusion and diffusion-weighted images were acquired at various times thereafter. The results showed that the drug reduced the size of the hyperintensity during the first hours, but did not affect the time constant of growth or the final size. The temporary reduction of the cytotoxic oedema induced by the torasemide derivative, demonstrates an antioedematous activity.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Aug
pubmed:issn
0304-3940
pubmed:author
pubmed:issnType
Print
pubmed:day
2
pubmed:volume
213
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
123-6
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
1996
pubmed:articleTitle
Delayed progression of cytotoxic oedema in focal cerebral ischemia after treatment with a torasemide derivative: a diffusion-weighted magnetic resonance imaging study.
pubmed:affiliation
INSERM U 438, Hôpital Michallon, Grenoble, France.
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't