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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
4
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pubmed:dateCreated |
1996-10-24
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pubmed:databankReference |
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pubmed:abstractText |
Two genes (rpsL and rrs) with mutations associated with streptomycin resistance in Mycobacterium tuberculosis were characterized in 78 streptomycin-resistant and 61 streptomycin-susceptible isolates recovered from patients living in the United States, South America, Europe, Africa, and Asia. Fifty-four percent of the 78 resistant organisms had missense mutations in codon 43 of rpsL resulting in a K-43-->R substitution. Mutations in codon 88 of rpsL were also identified in four Asian isolates.
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pubmed:grant |
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pubmed:commentsCorrections |
http://linkedlifedata.com/resource/pubmed/commentcorrection/8849220-2472961,
http://linkedlifedata.com/resource/pubmed/commentcorrection/8849220-2477554,
http://linkedlifedata.com/resource/pubmed/commentcorrection/8849220-4560854,
http://linkedlifedata.com/resource/pubmed/commentcorrection/8849220-6206780,
http://linkedlifedata.com/resource/pubmed/commentcorrection/8849220-7621399,
http://linkedlifedata.com/resource/pubmed/commentcorrection/8849220-7684757,
http://linkedlifedata.com/resource/pubmed/commentcorrection/8849220-7706824,
http://linkedlifedata.com/resource/pubmed/commentcorrection/8849220-7848059,
http://linkedlifedata.com/resource/pubmed/commentcorrection/8849220-7914261,
http://linkedlifedata.com/resource/pubmed/commentcorrection/8849220-7934937,
http://linkedlifedata.com/resource/pubmed/commentcorrection/8849220-7968530,
http://linkedlifedata.com/resource/pubmed/commentcorrection/8849220-8080502,
http://linkedlifedata.com/resource/pubmed/commentcorrection/8849220-8192448,
http://linkedlifedata.com/resource/pubmed/commentcorrection/8849220-8192450,
http://linkedlifedata.com/resource/pubmed/commentcorrection/8849220-8665467
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Apr
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pubmed:issn |
0066-4804
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
40
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
1024-6
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pubmed:dateRevised |
2009-11-18
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pubmed:meshHeading |
pubmed-meshheading:8849220-Antibiotics, Antitubercular,
pubmed-meshheading:8849220-Base Sequence,
pubmed-meshheading:8849220-Molecular Sequence Data,
pubmed-meshheading:8849220-Mycobacterium tuberculosis,
pubmed-meshheading:8849220-RNA, Ribosomal, 16S,
pubmed-meshheading:8849220-Ribosomal Proteins,
pubmed-meshheading:8849220-Sequence Homology,
pubmed-meshheading:8849220-Streptomycin
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pubmed:year |
1996
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pubmed:articleTitle |
Characterization of rpsL and rrs mutations in streptomycin-resistant Mycobacterium tuberculosis isolates from diverse geographic localities.
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pubmed:affiliation |
Department of Pathology, Baylor College of Medicine, Houston, Texas 77030, USA.
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pubmed:publicationType |
Journal Article,
Comparative Study,
Research Support, U.S. Gov't, P.H.S.
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