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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
3
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pubmed:dateCreated |
1996-10-24
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pubmed:abstractText |
Superselective transcatheter arterial radioembolization with radioiodinated lipiodol and gelatin sponges was evaluated in 11 patients with nodular hepatocellular carcinoma. Thirteen tumor nodules were treated using 3-5 ml of lipiodol labeled with 259 to 2220 MBq of I-131 followed by gelatin sponge with the following results: 1) there was elevated uptake in 12 tumor nodules with high tumor-to-background ratios: 2) there was excellent clinical tolerance to the treatment (stable cirrhosis in 5 patients and cirrhosis progression in 2 cases); 3) there was good disease control with size reduction in five tumor lesions (41%) and no increase in seven lesions (59%) followed for 2 years; 4) there was a 2-year survival rate of 70%; and 5) three deaths due to hepatic failure at 2, 3, and 20 months after therapy. Superselective arterial radioembolization with I-131 lipiodol is a useful palliative approach to inoperable hepatocarcinoma, providing long-term local control without severe complications in the progression of cirrhosis.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Mar
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pubmed:issn |
0363-9762
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
21
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
221-6
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pubmed:dateRevised |
2006-4-13
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pubmed:meshHeading |
pubmed-meshheading:8846568-Aged,
pubmed-meshheading:8846568-Carcinoma, Hepatocellular,
pubmed-meshheading:8846568-Embolization, Therapeutic,
pubmed-meshheading:8846568-Female,
pubmed-meshheading:8846568-Follow-Up Studies,
pubmed-meshheading:8846568-Gelatin Sponge, Absorbable,
pubmed-meshheading:8846568-Humans,
pubmed-meshheading:8846568-Injections, Intra-Arterial,
pubmed-meshheading:8846568-Iodine Radioisotopes,
pubmed-meshheading:8846568-Iodized Oil,
pubmed-meshheading:8846568-Liver Cirrhosis,
pubmed-meshheading:8846568-Liver Neoplasms,
pubmed-meshheading:8846568-Male,
pubmed-meshheading:8846568-Palliative Care,
pubmed-meshheading:8846568-Radiotherapy Dosage,
pubmed-meshheading:8846568-Survival Rate,
pubmed-meshheading:8846568-Time Factors
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pubmed:year |
1996
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pubmed:articleTitle |
Superselective intra-arterial radiometabolic therapy with I-131 lipiodol in hepatocellular carcinoma.
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pubmed:affiliation |
Department of Nuclear Medicine, Regina Elena, National Cancer Institute, Rome, Italy.
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pubmed:publicationType |
Journal Article
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