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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
3
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pubmed:dateCreated |
1996-10-24
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pubmed:abstractText |
The appearance of radiotracer in the systemic circulation to document the visualization of the brain, kidneys, and spleen after intravenous administration of Tc-99m MAA indicates right-to-left shunts because MAA particles (20-60 microns) are supposedly trapped in the pulmonary bed (less than 15 microns). Six hypoxemia patients (1 male, 5 females; age range, 12-52 years) with intrapulmonary right-to-left shunts were evaluated by Tc-99m MAA dynamic perfusion imaging and total-body scans. Tc-99m MAA total-body imaging of the six patients with intrapulmonary right-to-left shunts (3 patients with chronic liver disease/cirrhosis of the liver and 3 patients with pulmonary arteriovenous fistulae) revealed significant radiotracer uptake in extrapulmonary organs such as the brain, kidneys, and spleen; a shunt ratio, estimated by a semiquantitative method, ranged from 17.8% to 52%. All dynamic pulmonary perfusion scans showed a normal sequence of cardiopulmonary flow without intracardiac shunts. Three patients with pulmonary arteriovenous fistulae underwent a second Tc-99m MAA total-body imaging after embolization therapy (2 patients) or lobectomy (1 patient). The result in lobectomized patients were negative for uptake in extrapulmonary organs; the two patients who underwent embolization therapy demonstrated only mild improvement. As a consequence of these findings, the authors conclude that Tc-99m MAA total-body imaging can be used for the diagnosis of intrapulmonary right-to-left shunts, as well as for the evaluation of postshunt therapy.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Mar
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pubmed:issn |
0363-9762
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
21
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
197-202
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pubmed:dateRevised |
2007-11-15
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pubmed:meshHeading |
pubmed-meshheading:8846563-Adult,
pubmed-meshheading:8846563-Anoxia,
pubmed-meshheading:8846563-Arteriovenous Fistula,
pubmed-meshheading:8846563-Arteriovenous Malformations,
pubmed-meshheading:8846563-Child,
pubmed-meshheading:8846563-Embolization, Therapeutic,
pubmed-meshheading:8846563-Female,
pubmed-meshheading:8846563-Humans,
pubmed-meshheading:8846563-Lung,
pubmed-meshheading:8846563-Male,
pubmed-meshheading:8846563-Middle Aged,
pubmed-meshheading:8846563-Pneumonectomy,
pubmed-meshheading:8846563-Pulmonary Artery,
pubmed-meshheading:8846563-Pulmonary Veins,
pubmed-meshheading:8846563-Technetium Tc 99m Aggregated Albumin
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pubmed:year |
1996
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pubmed:articleTitle |
Tc-99m MAA total-body imaging to detect intrapulmonary right-to-left shunts and to evaluate the therapeutic effect in pulmonary arteriovenous shunts.
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pubmed:affiliation |
Department of Nuclear Medicine, Peijing Union Medical College Hospital, Beijing, China.
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pubmed:publicationType |
Journal Article,
Comparative Study,
Case Reports
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