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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
2
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pubmed:dateCreated |
1997-1-8
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pubmed:abstractText |
This study addresses the hypothesis that the diminished constriction of renal arterioles to angiotensin II (Ang II) and norepinephrine (NE) in diabetic rats is due to elevated activity in the polyol pathway. This activity results in reduced incorporation of myo-inositol into membrane phospholipids and impaired signal transduction.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
http://linkedlifedata.com/resource/pubmed/chemical/Acetylcholine,
http://linkedlifedata.com/resource/pubmed/chemical/Angiotensin II,
http://linkedlifedata.com/resource/pubmed/chemical/Blood Glucose,
http://linkedlifedata.com/resource/pubmed/chemical/Dietary Carbohydrates,
http://linkedlifedata.com/resource/pubmed/chemical/Inositol,
http://linkedlifedata.com/resource/pubmed/chemical/Membrane Lipids,
http://linkedlifedata.com/resource/pubmed/chemical/Norepinephrine,
http://linkedlifedata.com/resource/pubmed/chemical/Phospholipids,
http://linkedlifedata.com/resource/pubmed/chemical/Renin,
http://linkedlifedata.com/resource/pubmed/chemical/Streptozocin,
http://linkedlifedata.com/resource/pubmed/chemical/Vasoconstrictor Agents
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pubmed:status |
MEDLINE
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pubmed:month |
Jun
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pubmed:issn |
1073-9688
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
3
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
191-8
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:8839441-Acetylcholine,
pubmed-meshheading:8839441-Angiotensin II,
pubmed-meshheading:8839441-Animals,
pubmed-meshheading:8839441-Arterioles,
pubmed-meshheading:8839441-Blood Glucose,
pubmed-meshheading:8839441-Diabetes Mellitus, Experimental,
pubmed-meshheading:8839441-Diabetic Nephropathies,
pubmed-meshheading:8839441-Dietary Carbohydrates,
pubmed-meshheading:8839441-Female,
pubmed-meshheading:8839441-Hydronephrosis,
pubmed-meshheading:8839441-Inositol,
pubmed-meshheading:8839441-Kidney,
pubmed-meshheading:8839441-Membrane Lipids,
pubmed-meshheading:8839441-Microcirculation,
pubmed-meshheading:8839441-Norepinephrine,
pubmed-meshheading:8839441-Phospholipids,
pubmed-meshheading:8839441-Rats,
pubmed-meshheading:8839441-Rats, Wistar,
pubmed-meshheading:8839441-Renin,
pubmed-meshheading:8839441-Streptozocin,
pubmed-meshheading:8839441-Vasoconstriction,
pubmed-meshheading:8839441-Vasoconstrictor Agents
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pubmed:year |
1996
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pubmed:articleTitle |
Dietary myo-inositol restores diabetic renal arteriolar reactivity to angiotensin II but not to norepinephrine.
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pubmed:affiliation |
Department of Physiology & Biophysics School of Medicine, University of Louisville, Kentucky, USA.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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