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| Predicate | Object |
|---|---|
| rdf:type | |
| lifeskim:mentions | |
| pubmed:issue |
7
|
| pubmed:dateCreated |
1996-12-16
|
| pubmed:abstractText |
The aim of this study was to evaluate the diagnostic efficacy of protected bronchoalveolar lavage (PBAL) in ventilator-associated pneumonia (VAP), and to determine the effect of antibiotic therapy on its microbiological and cytological results. We prospectively studied 102 episodes of suspected VAP in 93 patients. Subsequent follow-up confirmed VAP in 35 of the 102 (34%) cases. In 55 of the 102 (55%) VAP was ruled out, and the diagnosis remained undetermined in 12 of the 102 (12%) episodes. In the VAP group, 30 of the 35 (86%) PBAL (> or = 10(4) colony-forming units (cfu)-mL-1) cultures were positive. In the non-VAP group, 5 of the 55 (9%) PBAL cultures were positive. A Giemsa stain of PBAL samples was performed in 32 of the 35 cases of VAP. Intracellular organisms (ICO) were found in 24 of the 32 (75%) cases. Seven of the other eight cases without evidence of ICO were already on antibiotics. In the non-VAP group, ICO were present in only 1 out of 55 (2%) cases. The mean ICO was significantly higher in the group who had not received antibiotics when compared with those patients previously treated for less than 48 h (p < or = 0.01) and those treated for more than 48 h (p = 0.009). The sensitivity of protected bronchoalveolar lavage quantitative cultures was 87% and the specificity 91%. The sensitivity of cytological analysis for intracellular organisms was 75% and the specificity 98%. According to our results, if the patient is already on antibiotics, the direct examination of protected bronchoalveolar lavage fluid is less reliable, although still helpful.
|
| pubmed:commentsCorrections | |
| pubmed:language |
eng
|
| pubmed:journal | |
| pubmed:citationSubset |
IM
|
| pubmed:chemical | |
| pubmed:status |
MEDLINE
|
| pubmed:month |
Jul
|
| pubmed:issn |
0903-1936
|
| pubmed:author | |
| pubmed:issnType |
Print
|
| pubmed:volume |
9
|
| pubmed:owner |
NLM
|
| pubmed:authorsComplete |
Y
|
| pubmed:pagination |
1500-7
|
| pubmed:dateRevised |
2006-11-15
|
| pubmed:meshHeading |
pubmed-meshheading:8836666-Anti-Bacterial Agents,
pubmed-meshheading:8836666-Biopsy,
pubmed-meshheading:8836666-Bronchi,
pubmed-meshheading:8836666-Bronchoalveolar Lavage,
pubmed-meshheading:8836666-Bronchoalveolar Lavage Fluid,
pubmed-meshheading:8836666-Bronchoscopes,
pubmed-meshheading:8836666-Bronchoscopy,
pubmed-meshheading:8836666-Colony Count, Microbial,
pubmed-meshheading:8836666-Cross Infection,
pubmed-meshheading:8836666-Female,
pubmed-meshheading:8836666-Humans,
pubmed-meshheading:8836666-Male,
pubmed-meshheading:8836666-Middle Aged,
pubmed-meshheading:8836666-Pneumonia, Bacterial,
pubmed-meshheading:8836666-Prospective Studies,
pubmed-meshheading:8836666-Respiration, Artificial,
pubmed-meshheading:8836666-Sensitivity and Specificity,
pubmed-meshheading:8836666-Ventilators, Mechanical
|
| pubmed:year |
1996
|
| pubmed:articleTitle |
Protected bronchoalveolar lavage in the diagnosis of ventilator-associated pneumonia.
|
| pubmed:affiliation |
Servei de Pneumologia, Hospital de Bellvitge, Barcelona, Spain.
|
| pubmed:publicationType |
Journal Article,
Comparative Study,
Research Support, Non-U.S. Gov't
|