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pubmed-article:8833464pubmed:abstractTextAn experimental study was conducted in guinea pigs for the predictive assessment of the beryllium alloy hazard in occupational exposure of the skin to beryllium compounds. Guinea pigs were sensitized to beryllium sulfate according to the maximized Magnusson and Kligman test, and challenged with beryllium alloys and metallic copper, beryllium and aluminum samples. Results showed a delayed skin hypersensitivity reaction in 30 to 60% of pre-sensitized guinea pigs challenged with copper-beryllium alloys and aluminum-beryllium alloy. An inflammatory follicular reaction was induced by copper in both controls and pre-sensitized guinea pigs.lld:pubmed
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pubmed-article:8833464pubmed:dateRevised2003-11-14lld:pubmed
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pubmed-article:8833464pubmed:articleTitlePatch testing with beryllium alloy samples in guinea pigs.lld:pubmed
pubmed-article:8833464pubmed:affiliationInstitut National de Recherche et de Securite, Vandoeuvre, France.lld:pubmed
pubmed-article:8833464pubmed:publicationTypeJournal Articlelld:pubmed