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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
3
|
pubmed:dateCreated |
1996-12-10
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pubmed:abstractText |
Reduced physical activity leads, in female mice, to a reduction of the average and maximal life span. The average age at death of the inactive experimental group was 497 +/- 121 days (mean +/- S.D.) compared to 557 +/- 139 days in the active control group, and the six oldest inactive experimental mice died at age 732 +/- 50 days, while the six oldest active control mice died at 890 +/- 52 days. The restriction of mobility was connected with a higher growth rate and a higher body weight in spite of a significant decrease in food intake. In spite of a reduced food intake leading to a reduced whole body metabolism, the results show that mobility restriction shortens life span in female mice.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:status |
MEDLINE
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pubmed:month |
Jul
|
pubmed:issn |
0047-6374
|
pubmed:author | |
pubmed:issnType |
Print
|
pubmed:day |
17
|
pubmed:volume |
88
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
159-68
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:8819099-Analysis of Variance,
pubmed-meshheading:8819099-Animals,
pubmed-meshheading:8819099-Body Weight,
pubmed-meshheading:8819099-Eating,
pubmed-meshheading:8819099-Female,
pubmed-meshheading:8819099-Longevity,
pubmed-meshheading:8819099-Mice,
pubmed-meshheading:8819099-Mice, Inbred Strains,
pubmed-meshheading:8819099-Motor Activity,
pubmed-meshheading:8819099-Restraint, Physical
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pubmed:year |
1996
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pubmed:articleTitle |
The effect of reduced physical activity on longevity of mice.
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pubmed:affiliation |
Institute of Medical Chemistry and Pregl Laboratory, Karl-Franzens-Universität Graz, Austria.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
|