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| Predicate | Object |
|---|---|
| rdf:type | |
| lifeskim:mentions | |
| pubmed:dateCreated |
1996-10-21
|
| pubmed:abstractText |
1. Physical training has been proposed to increase vagal control of heart rate in chronic heart failure. We studied the effects of physical training on cardiovascular control in 6 moderate to severe heart failure (NYHA II-III) patients and 6 age matched normal controls in a randomized controlled cross over trial (Training vs Detraining). 2. Five weeks training (20 min/day, 5 days/week bicycle exercise) increased peak VO2 in both C (from 31.2 +/- 1.4 to 37.7 +/- 2.4 ml/kg/min p < 0.01) and CHF patients (from 12.16 +/- 2.2 to 14.13 +/- 2 ml/kg/min p < 0.05). The sympathovagal control of heart rate and sympathetic control of the resistance vessels was assessed by the power of the oscillations (LF:0.03-0.15 Hz index of sympathetic activity, HF: 0.18-0.35 Hz index of vagal activity) in RR interval, blood pressure (systolic and diastolic by Finapres) and respiration by autoregressive spectral analysis, during free and controlled breathing (15b/min), in order to increase vagal activity. 3. T increased heart rate vagal control both in C (LF/HF ratio fb to cb: (D) 1.73 +/- 0.35 to 1.19 +/- 0.43 p = NS: (T) 2.9 +/- 1.2 to 1.13 +/- 0.3 p < 0.05) and in CHF patients (LF/HF ratio fb to cb: (D) 2.05 +/- 0.56 to 1.24 +/- 0.21 p = NS; (T) 2.6 +/- 0.89 to 0.87 +/- 0.15 p < 0.05; and in cb HF%: 36.2 +/- 2.7 (D) to 46.2 +/- 4.8 (T) p < 0.05). Before T, the sympathetic modulation of peripheral vessels (% LF compared to total variability) was depressed in CHF vs C (SBP: 9 +/- 2 vs 42 +/- 12% p < 0.05; DBP: 29 +/- 7 vs 55 +/- 31%, p < 0.05), and increased significantly after T in CHF (SBP from 9 +/- 2 (D) to 19 +/- 5% (T) p < 0.05; DBP from 29 +/- 7 to 41 +/- 11% (T) p < 0.05). This suggests an overall increase of autonomic control, both vagal on the heart and sympathetic on the peripheral vessels, in CHF by physical training.
|
| pubmed:language |
eng
|
| pubmed:journal | |
| pubmed:citationSubset |
IM
|
| pubmed:status |
MEDLINE
|
| pubmed:issn |
0143-5221
|
| pubmed:author | |
| pubmed:issnType |
Print
|
| pubmed:volume |
91 Suppl
|
| pubmed:owner |
NLM
|
| pubmed:authorsComplete |
Y
|
| pubmed:pagination |
92-4
|
| pubmed:dateRevised |
2007-11-15
|
| pubmed:meshHeading |
pubmed-meshheading:8813840-Autonomic Nervous System,
pubmed-meshheading:8813840-Blood Pressure,
pubmed-meshheading:8813840-Chronic Disease,
pubmed-meshheading:8813840-Cross-Over Studies,
pubmed-meshheading:8813840-Electrocardiography,
pubmed-meshheading:8813840-Exercise,
pubmed-meshheading:8813840-Exercise Therapy,
pubmed-meshheading:8813840-Heart Failure,
pubmed-meshheading:8813840-Heart Rate,
pubmed-meshheading:8813840-Humans,
pubmed-meshheading:8813840-Male,
pubmed-meshheading:8813840-Middle Aged,
pubmed-meshheading:8813840-Parasympathetic Nervous System,
pubmed-meshheading:8813840-Signal Processing, Computer-Assisted,
pubmed-meshheading:8813840-Sympathetic Nervous System
|
| pubmed:year |
1996
|
| pubmed:articleTitle |
Physical training enhances sympathetic and parasympathetic control of heart rate and peripheral vessels in chronic heart failure.
|
| pubmed:affiliation |
Department of Internal Medicine, Policlinico S Matteo, IRCCS, University of Pavia, I, Italy.
|
| pubmed:publicationType |
Journal Article,
Clinical Trial,
Comparative Study,
Randomized Controlled Trial
|